University of Geneva
International Workshop on Consanguinity
|
International Workshop on Consanguinity
Schedule of the consanguinity workshop
Monday 3rd May
Tuesday 4th May
Wednesday 5th May
Thursday 6th May
Friday 7th May
Monday 3rd May
08:30
|
Registration and Introduction to the Workshop |
| 09 :00 |
The search for pathogenic variants in the human genome Professor Stylianos Antonarakis |
09:40 |
When, why, and how did consanguineous marriage become a significant issue in global health? ProfessorAlan Bittles |
10:20 |
coffee break |
10:50 |
Global prevalence rates of consanguinity, and the changing profile Professor Hanan Hamamy |
| 11:30 |
What we can learn from compound heterozygosity in children of consanguineous parents, affected by autosomal recessive disease
Professor Leo ten Kate |
12:10 |
Lunch break |
14:00 |
The role of consanguinity in determining the serial loss of genetic diversity Professor Cavalli-Sforza |
14:40 |
Risk assessment, examples of families seeking genetic counselling for consanguinity Dr Robin Bennett |
15:20 |
Consanguinity: Geneva experience in genetic counselling Dr Siv Fokstuen |
16:00 |
Coffee break |
| 16:30 |
Adam’s War: Reduction of consanguineous genetic risk through information, collaboration and consistency Melissa Bonnefin |
| 16:50 - 18:00 |
General discussion and discussion of contributions to Working Papers |
Tuesday 4th May
09:00 |
Genetic counselling in inbred populations, a community based approach ProfessorJoel Zlotogora |
09:40 |
Consanguinity and reproductive health: fertility, prenatal losses, infant and childhood mortality: Professor Alan Bittles |
| 10:20 |
Consanguinity and birth defects
Professor Hanan Hamamy |
11:00 |
coffee break |
11:30 |
Consanguineous marriages: determining factors and use of consanguinity data for genetic epidemiology studies Professor Giovanni Romeo |
12:10 |
Consanguinity and social structure part 1: Functions of and motivations for consanguineous marriage, with particular reference to contemporary transnational Pakistani marriages in Europe. Dr Alison Shaw |
12:50 |
Lunch break |
14:20 |
Consanguinity and learning disabilities Professor Andre Megarbane |
15:00 |
The dysmorphic patient: a clinical genetic approach Dr Armand Bottani |
15:40 |
coffee break |
| 16:10 |
Making the change: reducing the impact of genetic disorders in UK minority communities Dr Peter Corry |
16:30 |
From consanguinity to genetic therapy: innovative tools for this new decade Dr Bruno Reversade |
16:50 - 18:30 |
Discussion on Working Paper 1: Recommendations for standardized epidemiological research methodologies on consanguinity, Chair: Professor Alan Bittles |
Wednesday 5th May: morning lectures will be at WHO headquarters in Geneva
08:30 |
At WHO reception |
| 09:00 |
WHO work on reproductive health research capacity strengthening in the African and Eastern Mediterranean regions Dr Heli Bathija |
09 :40 |
Research synthesis
Dr Metin Gülmezoglu |
10.20 |
Epidemiological studies Dr João Paulo Dias De Souza |
11:00 |
Coffee break, Tour and lunch in WHO | 14:00 (at CMU) |
Biobanking issues and networking opportunities
Mr Steve Arsenault |
14:40 |
Consanguinity and premarital genetic counselling Professor Hanan Hamamy |
15:20 |
Coffee break |
| 15:50 |
“Pre- and post-test risks in consanguineous marriage: case studies”. Dr Michael Morris |
| 16:10 |
Counselling consanguineous couples: current difficulties and future vision for service provision Gulshan Karbani |
| 16:30 |
Do consanguineous parents of children affected by autosomal recessive disease share more DNA than similarly related parents with healthy offspring? Background and design of a case-control study Dr Marieke Teeuw |
| 16:50 |
Prospective cohort and DNA-bank of consanguineous couples. A proposal. Professor Leo ten Kate |
| 17:10 |
Consanguinity and non-syndromic autism: preliminary report and prospects for future studies in highly consanguineous populations Dr Khalid Alwasiyah |
| 17:30 - 18:30 |
Discussion on Working Paper 2: Recommendations for research into social aspects of consanguinity, Chair: Dr Alison Shaw |
Thursday 6th May
09:00
|
Quantitative genetics in humans Professor Emmanouil Dermitzakis |
09:40 |
Consanguinity and the media, public concepts and misunderstandings, what messages to deliver to the public and to politicians
DrRobin Bennett |
| 10:20 |
Genetic screening in inbred populations Professor Joel Zlotogora |
| 11:00
|
Coffee break |
| 11:30 |
Consanguinity: The perspective of a genetic epidemiologist Professor Cornelia van Duijn |
12:10 |
Consanguinity and Down syndrome Dr Sophie Dahoun |
12:30 |
Lunch break |
| 14:00 |
Consanguinity and social structure part 2: Legal and ethical issues confronting consanguineous couples, with particular reference to receiving genetic risk information and the pre- or post-natal diagnosis of genetic problems in children Dr Alison Shaw |
14:40 |
Consanguinity & genetic disorders: Egyptian experience Professor Mona Aglan |
15:00 |
Consanguinity in the South Asian Population: comparative study of Britain and Canada Mubasshir Ajaz |
15:20 |
Coffee break |
| 15:50 |
Estimating disease allele frequencies from mutational records in autosomal recessive disorders Tomaso Pippucci |
| 16:10 |
Ethical challenges in genetic counselling of consanguineous families Rawan Awwad |
| 16:30 - 18:00 |
Discussion on Working Paper 3: Recommendations for genetic counselling and screening on consanguinity, Chair: Dr Robin Bennett |
Friday 7th May
09:00 |
Studies of the Human Genome in the 21st century
Normal genetic variation/genes and health, Genetic disorders and genetic predisposition to disease Professor Emmanouil Dermitzakis |
| 09:40 |
Homozygozity mapping in consanguineous families, the problem of genetic heterogeneity
ProfessorJoel Zlotogora |
| 10:20 |
Consanguinity and rare recessive disorders in Egypt Professor Samia Temtamy |
11:00 |
Coffee break |
11:30 |
Critical appraisal of the scientific and medical literature on consanguinity
Standardization of methodologies in consanguinity research ProfessorAlan Bittles |
| 12:10 |
Prenatal diagnosis in consanguineous Pakistani families Saghira Malik |
12:30 |
Lunch break |
14:00 |
Consanguinity and adult onset diseases Professors Alan Bittles, Hanan Hamamy |
14:20 |
Public Views towards Consanguinity in relation to Mental Illness in Iraq Dr Ayad AlKalamchi |
14:40 |
Evaluation of Odd Ratio (OR) and Relative Risk (RR) for Type 2 Diabetes in Relation to Consanguinity in Saudi Population Dr Dehkra AlNaqeb |
15:00 |
Discussion on Working Paper 4: Recommendations for educational initiatives to increase understanding on consanguinity, Chair : Professor Hanan Hamamy |
| 16:00 |
Coffee break |
16:30 |
Closing session Decisions on possible future research projects ‘Round table’ discussion of Faculty and Fellows Assessment |