BASIC MEDICAL SCIENCE: MICROBIOLOGY AND MOLECULAR MEDICINE
The Department of Microbiology and Molecular Medicine contributes to the understanding of the human body functions and dysfunctions through the study of microorganisms, be they pathogenic or be they part of model systems.
Part of the Department studies basic molecular mechanisms - as transcriptional regulation, ribosome biogenesis, RNA degradation, protein folding, ubiquitination, membrane organization, endocytosis, cell proliferation control - using as model systems Escherichia coli, Saccharomyces cerevisiae, mammalian cell lines or human primary cell lines. These topics concern the groups of M. Collart, J. Curran, C. Georgopoulos, P. Linder, M. Strubin and C. de Virgilio.
The other part studies the cellular and molecular biology of pathogens and their interactions with the infected host. These pathogens include bacteria, viruses and parasites. The research topics include the innate immunity directed against viruses and bacteria, their mode of entry and their motility, their metabolism and genetic expression and the response of the infected host. The groups of D. Kolakofsky, J. Pugin, V. Piguet, L. Roux, D. Soldati, M. Strubin and C. van Delden are concerned with these themes.
RESEARCH GROUPS |
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Director of the department : Prof. Laurent ROUX |
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