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Prof. Patrick LINDER


Rue Michel-Servet 1
1211 Geneva 4

Tel.: 022 379 56 60

CEBUG website


The Department of Microbiology and Molecular Medicine contributes to the understanding of the human body functions and dysfunctions through the study of microorganisms, be they pathogenic or be they part of model systems.

Part of the Department studies basic molecular mechanisms - as transcriptional regulation, ribosome biogenesis, RNA degradation, protein folding, ubiquitination, membrane organization, endocytosis, cell proliferation control - using as model systems Escherichia coli, Saccharomyces cerevisiae, mammalian cell lines or human primary cell lines. These topics concern the groups of M. Collart, J. Curran, C. Georgopoulos, P. Linder, M. Strubin and P. Viollier.

The other part studies the cellular and molecular biology of pathogens and their interactions with the infected host. These pathogens include bacteria, viruses and parasites. The research topics include the innate immunity directed against viruses and bacteria, their mode of entry and their motility, their metabolism and genetic expression and the response of the infected host. The groups of P. Linder, P. Viollier, J. Pugin, L. Roux, D. Soldati, M. Strubin and C. van Delden are concerned with these themes.

Translational Research:

Download the brochure about "Host-Pathogen Interactions" at the Faculty of medicine of UNIGE.


Head of Department: Prof. Patrick LINDER
Microbiology and Molecular Medicine
Regulation of transcripion initiation in the yeast S. cerevisiae
Eukaryotic translation initiation
  Molecular virology and innate immunity
  Acquisition and expression of virulence factors in Staphylococcus aureus.
The biology of an obligate intracellular parasite
Coding genes
  Asymmetric division in Caulobacter crescentus
Affiliated clinical groups
  Recognition of bacteria by innate immunity receptors
Quorom-sensing dependant virulence genes