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BASE DE DONNÉES-RECHERCHE | |
GROUPE DE RECHERCHE CLINIQUE ORIENTEE BIOLOGIE | ||||
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Patrik VUILLEUMIER | CV du Chef de Groupe | Sujet de Recherche | Composition du Groupe | |||
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Coordonnées du groupe
Prof. P. VUILLEUMIER CMU/ Dpt NEUF Rue Michel-Servet 1 1211 Genève 4 patrik.vuilleumier@unige.ch Tél.: + 41 22 379 53 81 Fax: + 41 22 379 54 02 Commentaires Pages générées le 16.05.2012 |
Sujet de recherche
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Publications du groupe
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Domaines de recherche
Mécanismes cérébraux du comportement et des fonctions cognitives
Notre laboratoire étudie les mécanismes cérébraux du comportement et des fonctions cognitives, chez des sujets normaux et chez des patients neurologiques atteints de lésions cérébrales focales. Notre
recherche concerne en particulier les mécanismes d'attention; la représentation de l'espace; la reconnaissance visuelle des objets et des visages; ainsi que les processus émotionnels et leurs
interactions avec d'autres fonctions cognitives. Un thème de recherche prioritaire concerne le syndrome de négligence spatiale et les troubles associés, tels que extinction perceptive et/ou motrice,
anosognosie, et perception inconsciente.
Un but commun dans ces différents domaines est de mieux comprendre comment différentes régions du cerveau qui sont chacune spécialisées dans l'analyse de différents signaux sensoriels peuvent influencer le fonctionnement des autres régions auxquelles elles sont interconnectées. Par exemple, les patients souffrant de négligence spatiale présentent une perte de perception consciente et d'exploration concernant tous les stimuli dans l'espace opposé à leur lésion (quelle que soit la modalité: visuelle, auditive, etc), même si leur lésion n'atteint pas des aires "sensorielles": ceci suggère que l'activité des régions pariétales (le plus souvent atteinte) joue un rôle majeur influençant l'analyse sensorielle et permettant une représentation consciente des stimuli. De façon similaire, l'analyse de signaux émotionnels dans des régions limbiques (par exemple l'expression émotionnelle ou la direction du regard dans un visage activant l'amygdale) semble capable d'influencer de nombreux processus perceptifs, attentionnels, et mnésiques (par exemple, via des processus de modulation ré-entrants). Notre approche utilise un ensemble de méthodes complémentaires: principalement mesures psychophysiques / comportementales, et neuroimagerie par résonance magnétique fonctionelle (IRMf), aussi bien chez les sujets normaux et les patients neuropsychologiques. Nous collaborons étroitement avec le Laboratoire de Cartographie des Fonctions Cérébrales pour l'utilisation des potentiels évoqués; l'Unité de Neuropsychologie de la Clinique de Neurologie; et le Service de Rééducation de Beau-Séjour. Le laboratoire est lié aux départements des Neurosciences Cliniques et de Physiologie de la Faculté de Médecine, et à la Faculté de Psychologie. Publications du groupe EEG-MEG evidence for early differential repetition effects for fearful happy and neutral faces BRAIN RESEARCH 2009 vol. 1254 pp. 84-98 MOREL S, PONZ A, MERCIER M, VUILLEUMIER P, GEORGE N Object Representations for Multiple Visual Categories Overlap in Lateral Occipital and Medial Fusiform Cortex CEREBRAL CORTEX 2009 vol. 19(8) pp. 1806-1819 POURTOIS G, SCHWARTZ S, SPIRIDON M, MARTUZZI R, VUILLEUMIER P Decoding of Emotional Information in Voice-Sensitive Cortices CURRENT BIOLOGY : CB 2009 vol. 19(12) pp. 1028-1033 ETHOFER T, VAN DE VILLE D, SCHERER KLAUS R., VUILLEUMIER P Differential development of selectivity for faces and bodies in the fusiform gyrus. DEVELOPMENTAL SCIENCE 2009 vol. 12(6) pp. 16-25 PEELEN MV, GLASER B, VUILLEUMIER P, ELIEZ S Attentional Load Modifies Early Activity in Human Primary Visual Cortex HUMAN BRAIN MAPPING 2009 vol. 30(5) pp. 1723-1733 RAUSS K, POURTOIS G, VUILLEUMIER P, SCHWARTZ S Functional Brain Imaging in a Woman With Spatial Neglect Due to Conversion Disorder JAMA 2009 vol. 302(23) pp. 2552-2554 SAJ A, ARZY S, VUILLEUMIER P Differential Influences of Emotion Task and Novelty on Brain Regions Underlying the Processing of Speech Melody JOURNAL OF COGNITIVE NEUROSCIENCE 2009 vol. 21(7) pp. 1255-1268 ETHOFER T, KREIFELTS B, WIETHOFF S, WOLF J, GRODD W, VUILLEUMIER P, WILDGRUBER D Dynamic Changes in Brain Activity during Prism Adaptation JOURNAL OF NEUROSCIENCE 2009 vol. 29(1) pp. 169-178 LUAUTE J, SCHWARTZ S, ROSSETTI Y, SPIRIDON M, RODE G, BOISSON D, VUILLEUMIER P Motor inhibition in hysterical conversion paralysis NEUROIMAGE 2009 vol. 47(3) pp. 1026-1037 COJAN Y, WABER L, CARRUZZO A, VUILLEUMIER P The Brain under Self-Control: Modulation of Inhibitory and Monitoring Cortical Networks during Hypnotic Paralysis NEURON 2009 vol. 62(6) pp. 862-875 COJAN Y, WABER L, SCHWARTZ S, ROSSIER L, FORSTER A, VUILLEUMIER P Emotional attention in acquired prosopagnosia. SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE 2009 vol. 4(3) pp. 268-277 PEELEN M, LUCAS N, MAYER E, VUILLEUMIER P Memory for friends or foes: The social context of past encounters with faces modulates their subsequent neural traces in the brain SOCIAL NEUROSCIENCE 2009 vol. 4(5) pp. 384-401 VRTICKA P, ANDERSSON F, SANDER D, VUILLEUMIER P Impaired activation of face processing networks revealed by functional magnetic resonance imaging in 22q11.2 deletion syndrome. BIOLOGICAL PSYCHIATRY 2008 vol. 63(1) pp. 49-57 ANDERSSON F, GLASER BRONWYN, SPIRIDON M, DEBBANE MARTIN, VUILLEUMIER P, ELIEZ S Bayesian models of mentalizing. BRAIN TOPOGRAPHY 2008 vol. 20(4) pp. 278-283 GRAVE DE PERALTA MENENDEZ R, ACHAIBOU A, BESSIERE P, VUILLEUMIER P, GONZALEZ ANDINO SARA Beyond conventional event-related brain potential (ERP): exploring the time-course of visual emotion processing using topographic and principal component analyses. BRAIN TOPOGRAPHY 2008 vol. 20(4) pp. 265-277 POURTOIS G, DELPLANQUE S, MICHEL CM, VUILLEUMIER P Abnormal attentional modulation of retinotopic cortex in parietal patients with spatial neglect. CURRENT BIOLOGY 2008 vol. 18(19) pp. 1525-1529 VUILLEUMIER P, SCHWARTZ S, VERDON VINCENT, MARAVITA A, HUTTON C, HUSAIN M, DRIVER J Early neuronal responses in right limbic structures mediate harmony incongruity processing in musical experts. NEUROIMAGE 2008 vol. 42(4) pp. 1597-1608 JAMES CE, BRITZ J, VUILLEUMIER P, HAUERT C-A, MICHEL CM Effects of emotional and non-emotional cues on visual search in neglect patients: evidence for distinct sources of attentional guidance. NEUROPSYCHOLOGIA 2008 vol. 46(5) pp. 1401-1414 LUCAS N, VUILLEUMIER P Effects of emotional prosody on auditory extinction for voices in patients with spatial neglect NEUROPSYCHOLOGIA 2008 vol. 46(2) pp. 487-496 GRANDJEAN DIDIER MAURICE, SANDER DAVID, LUCAS NADIA, SCHERER KLAUS R., VUILLEUMIER P Simultaneous recording of EEG and facial muscle reactions during spontaneous emotional mimicry NEUROPSYCHOLOGIA 2008 vol. 46(4) pp. 1104-1113 ACHAIBOU A, POURTOIS GILLES, SCHWARTZ S, VUILLEUMIER P Unavoidable errors: a spatio-temporal analysis of time-course and neural sources of evoked potentials associated with error processing in a speeded task. NEUROPSYCHOLOGIA 2008 vol. 46(10) pp. 2545-2555 VOCAT R, POURTOIS G, VUILLEUMIER P Individual attachment style modulates human amygdala and striatum activation during social appraisal. PLOS ONE 2008 vol. pp. 2868- VRTICKA P, ANDERSSON F, GRANDJEAN DIDIER MAURICE, SANDER DAVID, VUILLEUMIER P Effects of perceptual learning on primary visual cortex activity in humans VISION RESEARCH 2008 vol. 48(1) pp. 55-62 POURTOIS G, RAUSS K, VUILLEUMIER P, SCHWARTZ S Moving with or without will: Functional neural correlates of alien hand syndrome ANNALS OF NEUROLOGY 2007 vol. 62 pp. 301-306 ASSAL, F, SCHWARTZ, S, VUILLEUMIER, P Distinct and convergent visual processing of high and low spatial frequency information in faces CEREBRAL CORTEX 2007 vol. 17 pp. 2713-2724 ROTSHTEIN, P, VUILLEUMIER, P, WINSTON, J, DRIVER, J, DOLAN, R Neural basis for priming of pop-out during visual search revealed with fMRI CEREBRAL CORTEX 2007 vol. 17 pp. 1612-1624 KRISTJANSSON A, VUILLEUMIER P, SCHWARTZ S, MACALUSO E, DRIVER J Neglect: remembering the space left behind CURRENT BIOLOGY 2007 vol. 17(24) pp. 1060-1062 SAJ ARNAUD, VUILLEUMIER PATRICK Impaired perceptual memory of locations across gaze-shifts in patients with unilateral spatial neglect JOURNAL OF COGNITIVE NEUROSCIENCE 2007 vol. 19(8) pp. 1388-1406 VUILLEUMIER PATRICK, SERGENT CLAIRE, SCHWARTZ SOPHIE, VALENZA NATHALIE, GIRARDI MICHELE, HUSAIN MASUD, DRIVER JON Looking at human eyes affects contralesional stimulus processing after right hemispheric stroke NEUROLOGY 2007 vol. 69 pp. 1619-1621 MARAVITA, A, POSTERARO, L, HUSAIN, M, VUILLEUMIER, P, SCHWARTZ, S, DRIVER, J Direct intracranial recording of body-selective responses in human extrastriate visual cortex NEUROPSYCHOLOGIA 2007 vol. 45 pp. 2621-2625 POURTOIS G, PEELEN MV, SPINELLI L, SEECK M, VUILLEUMIER P Distributed and interactive brain mechanisms during emotion face perception: Evidence from functional neuroimaging NEUROPSYCHOLOGIA 2007 vol. 45 pp. 174-194 VUILLEUMIER, P, POURTOIS, G Modulation of visual processing by attention and emotion: windows on causal interactions between human brain regions PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON. SERIES B: BIOLOGICAL SCIENCES 2007 vol. 362(1481) pp. 837-855 VUILLEUMIER PATRICK, DRIVER JON Structural changes to the fusiform gyrus: A cerebral marker for social impairments in 22q11.2 deletion syndrome? SCHIZOPHRENIA RESEARCH 2007 vol. 96 pp. 82-86 GLASER, B, SCHAER, M, BEMEY, S, DEBBANE, M, VUILLEUMIER, P, ELIEZ, S Time course of brain activity during change blindness and change awareness: Performance is predicted by neural events before change onset JOURNAL OF COGNITIVE NEUROSCIENCE 2006 vol. 18 pp. 2108-2129 POURTOIS G, DE PRETTO M, HAUERT CA, VUILLEUMIER P Neural systems for orienting attention to the location of threat signals: An event-related fMRI study NEUROIMAGE 2006 vol. 31 pp. 920-933 POURTOIS G, SCHWARTZ S, SEGHIER ML, LAZEYRAS F, VUILLEUMIER P Functional neuroimaging findings on the human perception of illusory contours NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS 2006 vol. 30 pp. 595-612 SEGHIER ML, VUILLEUMIER P Dynamics of emotional effects on spatial attention in the human visual cortex PROGRESS IN BRAIN RESEARCH 2006 vol. 156 pp. 67-91 POURTOIS GILLES, VUILLEUMIER PATRIK Illusory persistence of touch after right parietal damage: neural correlates of tactile awareness BRAIN 2005 vol. 128 pp. 277-290 SCHWARTZ SOPHIE, ASSAL FREDERIC, VALENZA NATHALIE, SEGHIER MOHAMED, VUILLEUMIER PATRIK Attentional Load and Sensory Competition in Human Vision: Modulation of fMRI Responses by Load at Fixation during Task-irrelevant Stimulation in the Peripheral Visual Field. CEREBRAL CORTEX 2005 vol. 15 pp. 770-786 SCHWARTZ VUILLEUMIER SOPHIE, VUILLEUMIER PATRIK, HUTTON C., MARAVITA A., DOLAN R. J., DRIVER J. The involvement of distinct visual channels in rapid orienting toward fearful facial expressions COGNITION AND EMOTION 2005 vol. 19 pp. 899-922 HOLMES A, GREEN S, VUILLEUMIER PATRIK Enhanced Extrastriate Visual Response to Bandpass Spatial Frequency Filtered Fearful Faces : Time Course and Topographic Evoked-Potentials Mapping. HUMAN BRAIN MAPPING 2005 vol. 26 pp. 65-79 POURTOIS GILLES, DAN E. S., GRANDJEAN DIDIER MAURICE, SANDER D., VUILLEUMIER PATRIK Portraits or People ? Distinct Representations of Face Identity in the Human Visual Cortex. JOURNAL OF COGNITIVE NEUROSCIENCE 2005 vol. 17 pp. 1043-1057 POURTOIS GILLES, SCHWARTZ VUILLEUMIER SOPHIE, SEGHIER MOHAMED, LAZEYRAS FRANCOIS, VUILLEUMIER PATRIK Priming by color and location during visual search in unilateral spatial neflect. JOURNAL OF COGNITIVE NEUROSCIENCE 2005 vol. 17 pp. 859-873 KRISTJĀNSSON P., VUILLEUMIER PATRIK, MALHOTRA P, HUSAIN M, DRIVER J Selective Attention Modulates Neural Substrates of Repetition Priming and Implicit Visual Memory: Suppressions and Enhancements Revealed by fMRI. JOURNAL OF COGNITIVE NEUROSCIENCE 2005 vol. 17 pp. 1245-1260 VUILLEUMIER PATRIK, SCHWARTZ SOPHIE, DUHOUX S., DOLAN R. J., DRIVER J. Staring fear in the face. NATURE 2005 vol. 433 pp. 22-23 VUILLEUMIER PATRIK The voices of wrath: brain responses to angry prosody in meaningless speech. NATURE NEUROSCIENCE 2005 vol. 8 pp. 145-146 GRANDJEAN DIDIER MAURICE, SANDER DAVID, POURTOIS GILLES, SCHWARTZ VUILLEUMIER SOPHIE, SEGHIER MOHAMED, SCHERER KLAUS R., VUILLEUMIER PATRIK Emotion and attention interactions in social cognition: Brain regions involved in processing anger prosody. NEUROIMAGE 2005 vol. 28 pp. 848-858 SANDER D., GRANDJEAN D., POURTOIS GILLES, SCHWARTZ VUILLEUMIER SOPHIE, SEGHIER MOHAMED, SCHERER K. R., VUILLEUMIER PATRIK Hemispheric specialization of human inferior temporal cortex during coarse-to-fine and fine-to-coarse analysis of natural visual scenes. NEUROIMAGE 2005 vol. 28 pp. 464-473 PEYRIN C., SCHWARTZ VUILLEUMIER SOPHIE, SEGHIER MOHAMED, MICHEL CHRISTOPH, LANDIS THEODOR, VUILLEUMIER PATRIK Two electrophysiological stages of spatial orienting towards fearful faces : Early temporo-parietal activation preceding gain control in extrastriate visual cortex. NEUROIMAGE 2005 vol. 26 pp. 149-163 POURTOIS GILLES, THUT GREGOR, GRAVE DE PERALTA MENENDEZ R, MICHEL CHRISTOPH, VUILLEUMIER PATRIK View-independent coding of face identity in frontal and temporal cortices is modulated by familiarity: an event-related fMRI study NEUROIMAGE 2005 vol. 24 pp. 1214-1224 POURTOIS GILLES, SCHWARTZ VUILLEUMIER SOPHIE, SEGHIER MOHAMED, LAZEYRAS FRANCOIS, VUILLEUMIER PATRIK Functional Magnetic Resonance Imaging and Diffusion Tensor Imaging in a Case of Central Poststroke Pain. PAIN 2005 vol. 6 pp. 208-212 SEGHIER MOHAMED, LAZEYRAS FRANCOIS, VUILLEUMIER PATRIK, SCHNIDER ARMIN, CAROTA ANTONIO Hysterical conversion and brain function. Progress in Brain Research. PROGRESS IN BRAIN RESEARCH 2005 vol. 150 pp. 309-329 VUILLEUMIER PATRIK How brains beware: neural mechanisms of emotional attention. TRENDS IN COGNITIVE SCIENCES 2005 vol. 9 pp. 585-594 VUILLEUMIER PATRIK Effects of perveived mutual gaze on face judgments and face recognition memory. VISUAL COGNITION 2005 vol. 12 pp. 85-102 VUILLEUMIER PATRIK, GEORGE N, LISTER V, ARMONY J, DRIVER J Tactile awareness and limb position in neglect: functional magnetic resonance imaging. ANNALS OF NEUROLOGY 2004 vol. 55 pp. 139-143 VALENZA NATHALIE, SEGHIER MOHAMED, SCHWARTZ VUILLEUMIER SOPHIE, LAZEYRAS FRANCOIS, VUILLEUMIER PATRIK Electrophysiological Correlates of Rapid Spatial Orienting Towards Fearful Faces. CEREBRAL CORTEX 2004 vol. 14 pp. 619-633 POURTOIS GILLES, GRANDJEAN D, SANDER D, VUILLEUMIER PATRIK Anosognosia: The Neurology of Beliefs and Uncertainties. CORTEX 2004 vol. 40 pp. 7-15 VUILLEUMIER PATRIK The Number Space and Neglet. CORTEX 2004 vol. 40 pp. 399-410 VUILLEUMIER PATRIK, ORTIGUE STEPHANIE, BRUGGER P Dissociable roles of the human somatosensory and superior temporal cortices for processing social face signals. European Journal of Neuroscience 1-9, 2004 EUROPEAN JOURNAL OF NEUROSCIENCE 2004 vol. 20 pp. 3507-35015 POURTOIS GILLES, SANDER D, ANDRES M, GRANDJEAN D, REVERET L, OLIVIER E., VUILLEUMIER PATRIK Distant influences of amygdala lesion on visual cortical activation during emotional face processing. NATURE NEUROSCIENCE 2004 vol. 7 pp. 1271-1278 VUILLEUMIER PATRIK, RICHARDSON M. P.,, ARMONY J. L.,, DRIVER J.,, DOLAN R. J. The effect or repetition lag on electrophysiological and haemodynamic correlates of visual object priming. NEUROIMAGE 2004 vol. 21 pp. 1674-1689 HENSON R. N., RYLANDS A., ROSS E., VUILLEUMIER PATRIK, RUGG M. D. The space of senses: impaired crossmodal interactions in a patient with Balint syndrome after bilateral parietal damage NEUROPSYCHOLOGIA 2004 vol. pp. 1737-1748 VALENZA NATHALIE, MURRAY MICAH, PTAK RADEK, VUILLEUMIER PATRIK Time course and specificity of event-related potentials to emotional expressions. NEUROREPORT 2004 vol. 15 pp. 211-216 ASHLEY V., VUILLEUMIER PATRIK, SWICK D. Are Impairments of Action Monitoring and Executive Control True Dissociative Dysfunctions in Patients With Schizophrenia? AMERICAN JOURNAL OF PSYCHIATRY 2003 vol. 160 pp. 1881-1883 TURKEN A. U., VUILLEUMIER P, MATHALON D. H., SWICK D., FORD J. M. Amygdala Automaticity in Emotional Processing. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 2003 vol. 985 pp. 348-355 DOLAN R. J., VUILLEUMIER P Hyperfamiliarity for unknown faces after left lateral temporo-occipital venous infarction : a double dissociation with prosopagnosia. BRAIN 2003 vol. 126 pp. 889-907 VUILLEUMIER P, MOHR C, VALENZA N, WETZEL C, LANDIS T The processing of emotional facial expression is gated by spatial attention : evidence from event-related brain potentials. COGNITIVE BRAIN RESEARCH 2003 vol. 16 pp. 174-184 HOLMES A., VUILLEUMIER P., EIMER M. Effects of Low-Spatial Frequency Components of Fearful Faces on Fusiform Cortex Activity. CURRENT BIOLOGY 2003 vol. 13 pp. 1824-1829 WINSTON J. S., VUILLEUMIER P, DOLAN R. Effects of Attention and Emotion on Repetition Priming and Their Modulation by Cholinergic Enhancement. JOURNAL OF NEUROPHYSIOLOGY 2003 vol. 90 pp. 1171-1181 BENTLEY P., VUILLEUMIER P., THIEL C. M., DRIVER J., DOLAN R. J. Distinct spatial frequency sensitivities for processing faces and emotional expressions. NATURE NEUROSCIENCE 2003 vol. 6 pp. 624-631 VUILLEUMIER P, ARMONY J. L., DRIVER J., DOLAN R. J. Cholinergic enhancement modulates neural correlates of selective attention and emotional processing. NEUROIMAGE 2003 vol. 20 pp. 58-70 BENTLEY P., VUILLEUMIER P, THIEL C. M., DRIVER J., DOLAN R. J. Visual consciousness in health and disease. NEUROLOGIC CLINICS 2003 vol. 21 pp. 647-686 WHATHAM AR, VUILLEUMIER P, LANDIS T, SAFRAN A.B. Multiple levels of visual object constancy revealed by event-related fMRI of repetition priming NATURE NEUROSCIENCE 2002 vol. 5 pp. 491-499 VUILLEUMIER P., HENSON RN, DRIVER J, DOLAN RJ Neural fate of seen and unseen faces in unilateral spatial neglect: A combined event-related fMRI and ERP study of visual extinction PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2001 vol. 98 pp. 3495-3500 VUILLEUMIER PATRIK, SAGIV N, HAZELTINE E, POLDRACK R, SWICK D, RAFAL R, GABRIELI J Both means more than two: localizing and counting in patients with visuospatial neglect NATURE NEUROSCIENCE 1999 vol. 2 pp. 783-784 VUILLEUMIER PATRIK, RAFAL R Domaines de recherche |