Welcome in the research database

Clinical Virology

Our group is involved in the field of clinical virology with special focus on respiratory viruses and viral infections in immunocompromised hosts. We have investigated the role of respiratory viruses in different populations, but we have been particularly interested in immunocompromised hosts hospitalized with lower respiratory tract infections. In the community we have also analyzed the relations between influenza, antivirals, and antibiotic overuse. In order to better understand the impact of respiratory viruses we have developed and validated a large panel of tests aiming to identify respiratory viruses that commonly infect humans (real-time PCR, culture, serology, antigen detection, culture). These tests need to overcome the wide diversity of the different subtypes and serotypes causing diseases and we have carefully investigated the variability of respiratory viruses circulating in the community, particularly rhinovirus and influenza (by sequencing circulating strains and by hemagglutination inhibition assays). Our group functions as a reference laboratory for influenza and SARS surveillance in Switzerland in close collaboration with the Swiss Federal Office of Public Health and WHO (www.influenza.ch) and is involved in the surveillance of emerging viruses. Our research activities include also cytomegalovirus infections in transplant recipients. By developing ultrasensitive assays we have been able to better describe the kinetic of CMV replication in transplant recipients.

Group's publications

African descent is associated with slower CD4 cell count decline in treatment-naive patients of the Swiss HIV Cohort Study.
AIDS
2009 vol. 23(10) pp. 1269-1276
MÜLLER V AND AL.

The impact of transmission clusters on primary drug resistance in newly diagnosed HIV-1 infection
AIDS
2009 vol. 23(11) pp. 1415-1423
YERLY S AND AL.

New respiratory enterovirus and recombinant rhinoviruses among circulating picornaviruses.
EMERGING INFECTIOUS DISEASES (PRINT)
2009 vol. 15(5) pp. 719-726
TAPPAREL C AND AL.

Etiology of community-acquired pneumonia in hospitalized children based on WHO clinical guidelines
EUROPEAN JOURNAL OF PEDIATRICS
2009 vol. 168(12) pp. 1429-1436
CEVEY-MACHEREL M, GALETTO-LACOUR A, GERVAIX A, SIEGRIST CA, BILLE J, BESCHER-NINET B, KAISER L, KRAHENBUHL JD, GEHRI M

Liver enzyme elevation after lamivudine withdrawal in HIV-hepatitis B virus co-infected patients: the Swiss HIV Cohort Study.
HIV MEDICINE
2009 vol. 10(1) pp. 12-18
BELLINI C. AND AL.

New Molecular Detection Tools Adapted to Emerging Rhinoviruses and Enteroviruses
JOURNAL OF CLINICAL MICROBIOLOGY
2009 vol. 47(6) pp. 1742-1749
TAPPAREL C, CORDEY S, VAN BELLE S, TURIN L, LEE WM, REGAMEY N, MEYLAN P, MÜHLEMANN K, GOBBINI F, KAISER L

Pneumonia and pericarditis in a child with HRV-C infection: A case report
JOURNAL OF CLINICAL VIROLOGY
2009 vol. 45(2) pp. 157-160
TAPPAREL C, L'HUILLIER AG, ROUGEMONT AL, BEGHETTI M, BARAZZONE-ARGIROFFO C, KAISER L

High prevalence of non-B HIV-1 subtypes in seamen and their sexual partners in Croatia.
JOURNAL OF MEDICAL VIROLOGY
2009 vol. 81(4) pp. 573-577
RAMIREZ-PIEDAD MK, LEPEJ SZ, YERLY S, BEGOVAC J

Simultaneous detection of parainfluenza viruses 1 and 3 by real-time reverse transcription-polymerase chain reaction
JOURNAL OF VIROLOGICAL METHODS
2009 vol. 156 pp. 166-168
CORDEY S, THOMAS Y, CHERPILLOD P, VAN BELLE S, TAPPAREL C, KAISER L

An influenza smiley.
SWISS MEDICAL WEEKLY
2009 vol. 139(21-22) pp. 298-299
KAISER L

Respiratory viruses in bronchoalveolar lavage: a hospital-based cohort study in adults.
THORAX
2009 vol. 64(5) pp. 399-404
GARBINO J, SOCCAL PAOLA MARINA, AUBERT JD, ROCHAT T, MEYLAN P, THOMAS Y, TAPPAREL C, BRIDEVAUX PO, KAISER L

Respiratory viruses in HIV-infected patients with suspected respiratory opportunistic infection.
AIDS
2008 vol. 22(6) pp. 701-705
GARBINO J, INOUBLI S, MOSSDORF E, WEBER R, TAMM M, SOCCAL PAOLA MARINA, AUBERT JD, BRIDEVAUX PO, TAPPAREL C, KAISER L

Natural killer cell receptor repertoire and their ligands, and the risk of CMV infection after kidney transplantation.
AMERICAN JOURNAL OF TRANSPLANTATION
2008 vol. 8(12) pp. 2674-2683
HADAYA K, DE RHAM C, BANDELIER C, BANDELIER CH, FERRARI-LACRAZ SYLVIE, JENDLY S, BERNEY T, BUHLER L, KAISER L, SEEBACH J, TIERCY JM, MARTIN PY, VILLARD J

Survival of influenza virus on banknotes.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
2008 vol. 74(10) pp. 3002-3007
THOMAS Y, VOGEL G, WUNDERLI W, SUTER P, WITSCHI M, KOCH D, TAPPAREL C, KAISER L

Value of a novel Neisseria meningitidis--specific polymerase chain reaction assay in skin biopsy specimens as a diagnostic tool in chronic meningococcemia.
ARCHIVES OF DERMATOLOGY
2008 vol. 144(6) pp. 770-773
PARMENTIER L, GARZONI CHRISTIAN, ANTILLE C, KAISER L, NINET B, BORRADORI L

Factors associated with the emergence of K65R in patients with HIV-1 infection treated with combination antiretroviral therapy containing tenofovir.
CLINICAL INFECTIOUS DISEASES
2008 vol. 46(8) pp. 1299-1309
VON WYL V AND AL.

Use of the rapid antigenic test to determine the duration of isolation in infants hospitalized for respiratory syncytial virus infections.
CLINICAL PEDIATRICS
2008 vol. 47(5) pp. 493-495
MYERS C, WAGNER N, KAISER L, POSFAY-BARBE KLARA, GERVAIX A

National survey of the prevalence and conditions of selection of HIV-1 reverse transcriptase K70E mutation.
JOURNAL OF MEDICAL VIROLOGY
2008 vol. ;80(5) pp. 762-765
DELAUGERRE C AND AL.

Simultaneous detection of parainfluenza viruses 1 and 3 by real-time reverse transcription-polymerase chain reaction.
JOURNAL OF VIROLOGICAL METHODS
2008 vol. 156(1-2) pp. 166-168
CORDEY S, THOMAS Y, CHERPILLOD P, VAN BELLE S, TAPPAREL C, KAISER L

Antibiotics for adults with clinically diagnosed acute rhinosinusitis: a meta-analysis of individual patient data.
LANCET
2008 vol. 371(9616) pp. 908-914
YOUNG J, DE SUTTER A, MERENSTEIN D, VAN ESSEN GA, KAISER L, VARONEN H, WILLIAMSON I, BUCHER HC

Human herpesvirus-6 variant A encephalomyelitis.
NEUROLOGY
2008 vol. 70(12) pp. 974-976
POT C, BURKHARD PR, VILLARD J, PERRIN L, KAISER L, LANDIS T, LALIVE P.H.

Viral etiology of acute respiratory infections with cough in infancy: a community-based birth cohort study.
PEDIATRIC INFECTIOUS DISEASE JOURNAL
2008 vol. 27(2) pp. 100-105
REGAMEY NICOLAS, KAISER L, ROIHA HL, DEFFERNEZ C, KUEHNI C, LATZIN P, AEBI C, FREY U

Bronchoalveolar cytology for diagnosing pulmonary GVHD after bone marrow transplant in children.
PEDIATRIC PULMONOLOGY
2008 vol. 43(7) pp. 697-702
ROCHAT I, POSFAY-BARBE, KUMAR N, PACHE JC, KAISER L, OZSAHIN H, BARAZZONE-ARGIROFFO C, BONGIOVANNI MASSIMO

RIG-I and dsRNA-induced IFNbeta activation.
PLOS ONE
2008 vol. 3(12) pp. 3965-3965
HAUSMANN S, MARQ JB, TAPPAREL C, KOLAKOFSKY D, GARCIN D

The cis-acting replication elements define human enterovirus and rhinovirus species.
RNA (NEW YORK, N.Y.)
2008 vol. 14(8) pp. 1568-1578
CORDEY S, GERLACH D, JUNIER T, ZDOBNOV EVGENY, KAISER L, TAPPAREL C

HIV-1-infected patients from the French National Observatory experiencing virological failure while receiving enfuvirtide.
THE JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
2008 vol. 62(3) pp. 451-455
DESCAMPS D AND AL.

Transmission of HIV-1 drug resistance in Switzerland: a 10-year molecular epidemiology survey
AIDS
2007 vol. 21 pp. 2223-2229
YERLY, S, VON WYL, V, LEDERGERBER, B, BONI, J, SCHUPBACH, J, BURGISSER, P, KLIMKAIT, T, RICKENBACH, M, KAISER, L, GUNTHARD, HF, PERRIN, L

New complete genome sequences of human rhinoviruses shed light on their phylogeny and genomic features
BMC GENOMICS
2007 vol. 8 pp. 224-
TAPPAREL, C, JUNIER, T, GERLACH, D, CORDEY, S, VAN BELLE, S, PERRIN, L, ZDOBNOV, EM, KAISER, L

Age limit does not replace serologic testing for determination of immune status for measles
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
2007 vol. 28 pp. 1117-1120
UCKAY I, HUGONNET S, KAISER L, SAX HG, PITTET D

Generic detection of coronaviruses and differentiation at the prototype strain level by reverse transcription-PCR and nonfluorescent low-density microarray
JOURNAL OF CLINICAL MICROBIOLOGY
2007 vol. 45 pp. 1049-1052
LUNA LKD, HEISER V, REGAMEY N, PANNING M, DREXLER JF, MULANGU S, POON L, BAUMGARTE S, HAIJEMA BJ, KAISER L, DROSTEN C

Cytomegalovirus quantification in plasma by an automated real-time PCR assay
JOURNAL OF CLINICAL VIROLOGY
2007 vol. 38 pp. 298-303
YERLY, S, PERRIN, L, VAN DELDEN, C, SCHAFFER, S, THAMM, S, WUNDERLI, W, KAISER, L

Isolation of human bocavirus from swiss infants with respiratory infections
PEDIATRIC INFECTIOUS DISEASE JOURNAL
2007 vol. 26 pp. 177-179
REGAMEY N, FREY U, DEFFERNEZ C, LATZIN P, KAISER L

Influenza transmission to recipient through lung transplantation
TRANSPLANT INFECTIOUS DISEASE : AN OFFICIAL JOURNAL OF THE TRANSPLANTATION SOCIETY
2007 vol. 9(1) pp. 55-57
MEYLAN PR, AUBERT JD, KAISER L

Chronic rhinoviral infection in lung transplant recipients
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2006 vol. 174 pp. 1392-1399
KAISER L, AUBERT JD, PACHE JC, DEFFERNEZ C, ROCHAT T, GARBINO J, WUNDERLI W, MEYLAN P, YERLY S, PERRIN L, LETOVANEC I, NICOD L, TAPPAREL C, SOCCAL PM

Pretransplantation CMV-specific T cells protect recipients of T-cell-depleted grafts against CMV-related complications
BLOOD
2006 vol. 07(1) pp. 389-396
CHALANDON Y. ET AL.

A prospective hospital-based study of the clinical impact of non-severe acute respiratory syndrome (non-SARS)-related human coronavirus infection
CLINICAL INFECTIOUS DISEASES
2006 vol. 43 pp. 1009-1015
GARBINO J, CRESPO S, AUBERT JD, ROCHAT T, NINET B, DEFFERNEZ C, WUNDERLI W, PACHE JC, SOCCAL PM, KAISER L

Influenza will not miss opportunities
CLINICAL INFECTIOUS DISEASES
2006 vol. 43 pp. 1562-1564
KAISER L

Analysis of factors that contribute to treatment failure in patients with community-acquired pneumonia
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
2006 vol. 25 pp. 159-166
GENNE D, SOMMER R, KAISER L, SAAIDIA A, PASCHE A, UNGER P, LEW D

HIV and solid organ transplantation: The Swiss experience
SWISS MEDICAL WEEKLY
2006 vol. 136 pp. 194-196
MULLER NJ, HIRSCHEL B, FURRER H, KAISER L, CAVASSINI M, FELLAY J, CHAVE JP, WUTHRICH RP, WEBER M, MULLHAUPT B, CANDINAS D, REICHEN F, GIOSTRA E, MENTHA G, HALKIC N, HIRSCH HH, WEBER R

Portal vein thrombosis following a primary cytomegalovirus infection in an immunocompetent adult
THROMBOSIS AND HAEMOSTASIS
2006 vol. 95 pp. 199-201
GUEDDI S, RIGHINI M, MEZGER N, MORARD I, KAISER L, GIOSTRA E, BOUNAMEAUX H, ANGELILLO-SCHERRER A

Detection and quantification of nucleic acids in infections diseases: utility and limitations
REVUE MÉDICALE SUISSE
2005 vol. 1(13) pp. 887-890
YERLY S, KAISER L, NINET B

Consequences of an unsufficient range of immunity in "pediatric" infectious diseases--example with measles
THERAPEUTISCHE UMSCHAU : MONATSSCHRIFT FUER PRAKTISCHE MEDIZIN = REVUE THERAPEUTIQUE : REVUE MENSUELLE DE MEDECINE PRATIQUE
2005 vol. 62(10) pp. 679-684
UCKAY ILKER, SAX HUGO, HUGONNET STEPHANE, ARAMBURU C, BESSIRE N, RUTSCHMANN OLIVIER, KAISER LAURENT, GERVAIX ALAIN, SUDRE PHILIPPE, SIEGRIST CLAIRE-ANNE, PITTET DIDIER

Impact of oseltamivir treatment on influenza-related lower respiratory tract complications and hospitalisations.
ARCHIVES OF INTERNAL MEDICINE
2003 vol. 163 pp. 1667-1672
KAISER L, WAT CYNTHIA, MILLS TRACY, MAHONEY PAUL, WARD PENELOPE, HAYDEN FREDERICK

Monitoring of cytomegalovirus infection in solid-organ transplant recipients by an ultrasensitive plasma PCR assay
JOURNAL OF CLINICAL MICROBIOLOGY
2003 vol. 41 pp. 3757-3764
HADAYA K, WUNDERLI W, DEFFERNEZ C, MARTIN PY, MENTHA G, BINET I, PERRIN L, KAISER L

Improved monitoring of cytomegalovirus infection after allogeneic hematopoietic stem cell transplantation by an ultrasensitive plasma DNA PCR assay
JOURNAL OF CLINICAL MICROBIOLOGY
2002 vol. 40 pp. 4251-4255
KAISER L, PERRIN L, CHAPUIS B, HADAYA K, KOLAROVA L, DEFFERNEZ C, HUGUET S, HELG C, WUNDERLI W

Research's domains

TRANSPLANTATION
CLINICAL VIROLOGY
INFLUENZA SUPERVISION
RHINOVIRUS
RESPIRATORY VIRUSES




DATABASE-RESEARCH	GROUP OF CLINICAL PATIENT RESEARCH

Laurent KAISER	Head of group CV	Research subject	Members of the group


	Links about the group Prof. L. KAISER HUG/Spécialités de Médecine Laboratoire de virologie Rue Gabrielle-Perret-Gentil 4 1211 Genève 14 Suisse Laurent.kaiser@hcuge.ch Tel.: + 41 22 372 40 96 Fax: + 41 22 372 40 97 Comments Pages updated the 17.11.2015		Reseach's subject \| Group's publications \| Research's domains Clinical Virology Our group is involved in the field of clinical virology with special focus on respiratory viruses and viral infections in immunocompromised hosts. We have investigated the role of respiratory viruses in different populations, but we have been particularly interested in immunocompromised hosts hospitalized with lower respiratory tract infections. In the community we have also analyzed the relations between influenza, antivirals, and antibiotic overuse. In order to better understand the impact of respiratory viruses we have developed and validated a large panel of tests aiming to identify respiratory viruses that commonly infect humans (real-time PCR, culture, serology, antigen detection, culture). These tests need to overcome the wide diversity of the different subtypes and serotypes causing diseases and we have carefully investigated the variability of respiratory viruses circulating in the community, particularly rhinovirus and influenza (by sequencing circulating strains and by hemagglutination inhibition assays). Our group functions as a reference laboratory for influenza and SARS surveillance in Switzerland in close collaboration with the Swiss Federal Office of Public Health and WHO (www.influenza.ch) and is involved in the surveillance of emerging viruses. Our research activities include also cytomegalovirus infections in transplant recipients. By developing ultrasensitive assays we have been able to better describe the kinetic of CMV replication in transplant recipients. Group's publications African descent is associated with slower CD4 cell count decline in treatment-naive patients of the Swiss HIV Cohort Study. AIDS 2009 vol. 23(10) pp. 1269-1276 MÜLLER V AND AL. The impact of transmission clusters on primary drug resistance in newly diagnosed HIV-1 infection AIDS 2009 vol. 23(11) pp. 1415-1423 YERLY S AND AL. New respiratory enterovirus and recombinant rhinoviruses among circulating picornaviruses. EMERGING INFECTIOUS DISEASES (PRINT) 2009 vol. 15(5) pp. 719-726 TAPPAREL C AND AL. Etiology of community-acquired pneumonia in hospitalized children based on WHO clinical guidelines EUROPEAN JOURNAL OF PEDIATRICS 2009 vol. 168(12) pp. 1429-1436 CEVEY-MACHEREL M, GALETTO-LACOUR A, GERVAIX A, SIEGRIST CA, BILLE J, BESCHER-NINET B, KAISER L, KRAHENBUHL JD, GEHRI M Liver enzyme elevation after lamivudine withdrawal in HIV-hepatitis B virus co-infected patients: the Swiss HIV Cohort Study. HIV MEDICINE 2009 vol. 10(1) pp. 12-18 BELLINI C. AND AL. New Molecular Detection Tools Adapted to Emerging Rhinoviruses and Enteroviruses JOURNAL OF CLINICAL MICROBIOLOGY 2009 vol. 47(6) pp. 1742-1749 TAPPAREL C, CORDEY S, VAN BELLE S, TURIN L, LEE WM, REGAMEY N, MEYLAN P, MÜHLEMANN K, GOBBINI F, KAISER L Pneumonia and pericarditis in a child with HRV-C infection: A case report JOURNAL OF CLINICAL VIROLOGY 2009 vol. 45(2) pp. 157-160 TAPPAREL C, L'HUILLIER AG, ROUGEMONT AL, BEGHETTI M, BARAZZONE-ARGIROFFO C, KAISER L High prevalence of non-B HIV-1 subtypes in seamen and their sexual partners in Croatia. JOURNAL OF MEDICAL VIROLOGY 2009 vol. 81(4) pp. 573-577 RAMIREZ-PIEDAD MK, LEPEJ SZ, YERLY S, BEGOVAC J Simultaneous detection of parainfluenza viruses 1 and 3 by real-time reverse transcription-polymerase chain reaction JOURNAL OF VIROLOGICAL METHODS 2009 vol. 156 pp. 166-168 CORDEY S, THOMAS Y, CHERPILLOD P, VAN BELLE S, TAPPAREL C, KAISER L An influenza smiley. SWISS MEDICAL WEEKLY 2009 vol. 139(21-22) pp. 298-299 KAISER L Respiratory viruses in bronchoalveolar lavage: a hospital-based cohort study in adults. THORAX 2009 vol. 64(5) pp. 399-404 GARBINO J, SOCCAL PAOLA MARINA, AUBERT JD, ROCHAT T, MEYLAN P, THOMAS Y, TAPPAREL C, BRIDEVAUX PO, KAISER L Respiratory viruses in HIV-infected patients with suspected respiratory opportunistic infection. AIDS 2008 vol. 22(6) pp. 701-705 GARBINO J, INOUBLI S, MOSSDORF E, WEBER R, TAMM M, SOCCAL PAOLA MARINA, AUBERT JD, BRIDEVAUX PO, TAPPAREL C, KAISER L Natural killer cell receptor repertoire and their ligands, and the risk of CMV infection after kidney transplantation. AMERICAN JOURNAL OF TRANSPLANTATION 2008 vol. 8(12) pp. 2674-2683 HADAYA K, DE RHAM C, BANDELIER C, BANDELIER CH, FERRARI-LACRAZ SYLVIE, JENDLY S, BERNEY T, BUHLER L, KAISER L, SEEBACH J, TIERCY JM, MARTIN PY, VILLARD J Survival of influenza virus on banknotes. APPLIED AND ENVIRONMENTAL MICROBIOLOGY 2008 vol. 74(10) pp. 3002-3007 THOMAS Y, VOGEL G, WUNDERLI W, SUTER P, WITSCHI M, KOCH D, TAPPAREL C, KAISER L Value of a novel Neisseria meningitidis--specific polymerase chain reaction assay in skin biopsy specimens as a diagnostic tool in chronic meningococcemia. ARCHIVES OF DERMATOLOGY 2008 vol. 144(6) pp. 770-773 PARMENTIER L, GARZONI CHRISTIAN, ANTILLE C, KAISER L, NINET B, BORRADORI L Factors associated with the emergence of K65R in patients with HIV-1 infection treated with combination antiretroviral therapy containing tenofovir. CLINICAL INFECTIOUS DISEASES 2008 vol. 46(8) pp. 1299-1309 VON WYL V AND AL. Use of the rapid antigenic test to determine the duration of isolation in infants hospitalized for respiratory syncytial virus infections. CLINICAL PEDIATRICS 2008 vol. 47(5) pp. 493-495 MYERS C, WAGNER N, KAISER L, POSFAY-BARBE KLARA, GERVAIX A National survey of the prevalence and conditions of selection of HIV-1 reverse transcriptase K70E mutation. JOURNAL OF MEDICAL VIROLOGY 2008 vol. ;80(5) pp. 762-765 DELAUGERRE C AND AL. Simultaneous detection of parainfluenza viruses 1 and 3 by real-time reverse transcription-polymerase chain reaction. JOURNAL OF VIROLOGICAL METHODS 2008 vol. 156(1-2) pp. 166-168 CORDEY S, THOMAS Y, CHERPILLOD P, VAN BELLE S, TAPPAREL C, KAISER L Antibiotics for adults with clinically diagnosed acute rhinosinusitis: a meta-analysis of individual patient data. LANCET 2008 vol. 371(9616) pp. 908-914 YOUNG J, DE SUTTER A, MERENSTEIN D, VAN ESSEN GA, KAISER L, VARONEN H, WILLIAMSON I, BUCHER HC Human herpesvirus-6 variant A encephalomyelitis. NEUROLOGY 2008 vol. 70(12) pp. 974-976 POT C, BURKHARD PR, VILLARD J, PERRIN L, KAISER L, LANDIS T, LALIVE P.H. Viral etiology of acute respiratory infections with cough in infancy: a community-based birth cohort study. PEDIATRIC INFECTIOUS DISEASE JOURNAL 2008 vol. 27(2) pp. 100-105 REGAMEY NICOLAS, KAISER L, ROIHA HL, DEFFERNEZ C, KUEHNI C, LATZIN P, AEBI C, FREY U Bronchoalveolar cytology for diagnosing pulmonary GVHD after bone marrow transplant in children. PEDIATRIC PULMONOLOGY 2008 vol. 43(7) pp. 697-702 ROCHAT I, POSFAY-BARBE, KUMAR N, PACHE JC, KAISER L, OZSAHIN H, BARAZZONE-ARGIROFFO C, BONGIOVANNI MASSIMO RIG-I and dsRNA-induced IFNbeta activation. PLOS ONE 2008 vol. 3(12) pp. 3965-3965 HAUSMANN S, MARQ JB, TAPPAREL C, KOLAKOFSKY D, GARCIN D The cis-acting replication elements define human enterovirus and rhinovirus species. RNA (NEW YORK, N.Y.) 2008 vol. 14(8) pp. 1568-1578 CORDEY S, GERLACH D, JUNIER T, ZDOBNOV EVGENY, KAISER L, TAPPAREL C HIV-1-infected patients from the French National Observatory experiencing virological failure while receiving enfuvirtide. THE JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 2008 vol. 62(3) pp. 451-455 DESCAMPS D AND AL. Transmission of HIV-1 drug resistance in Switzerland: a 10-year molecular epidemiology survey AIDS 2007 vol. 21 pp. 2223-2229 YERLY, S, VON WYL, V, LEDERGERBER, B, BONI, J, SCHUPBACH, J, BURGISSER, P, KLIMKAIT, T, RICKENBACH, M, KAISER, L, GUNTHARD, HF, PERRIN, L New complete genome sequences of human rhinoviruses shed light on their phylogeny and genomic features BMC GENOMICS 2007 vol. 8 pp. 224- TAPPAREL, C, JUNIER, T, GERLACH, D, CORDEY, S, VAN BELLE, S, PERRIN, L, ZDOBNOV, EM, KAISER, L Age limit does not replace serologic testing for determination of immune status for measles INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY 2007 vol. 28 pp. 1117-1120 UCKAY I, HUGONNET S, KAISER L, SAX HG, PITTET D Generic detection of coronaviruses and differentiation at the prototype strain level by reverse transcription-PCR and nonfluorescent low-density microarray JOURNAL OF CLINICAL MICROBIOLOGY 2007 vol. 45 pp. 1049-1052 LUNA LKD, HEISER V, REGAMEY N, PANNING M, DREXLER JF, MULANGU S, POON L, BAUMGARTE S, HAIJEMA BJ, KAISER L, DROSTEN C Cytomegalovirus quantification in plasma by an automated real-time PCR assay JOURNAL OF CLINICAL VIROLOGY 2007 vol. 38 pp. 298-303 YERLY, S, PERRIN, L, VAN DELDEN, C, SCHAFFER, S, THAMM, S, WUNDERLI, W, KAISER, L Isolation of human bocavirus from swiss infants with respiratory infections PEDIATRIC INFECTIOUS DISEASE JOURNAL 2007 vol. 26 pp. 177-179 REGAMEY N, FREY U, DEFFERNEZ C, LATZIN P, KAISER L Influenza transmission to recipient through lung transplantation TRANSPLANT INFECTIOUS DISEASE : AN OFFICIAL JOURNAL OF THE TRANSPLANTATION SOCIETY 2007 vol. 9(1) pp. 55-57 MEYLAN PR, AUBERT JD, KAISER L Chronic rhinoviral infection in lung transplant recipients AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 2006 vol. 174 pp. 1392-1399 KAISER L, AUBERT JD, PACHE JC, DEFFERNEZ C, ROCHAT T, GARBINO J, WUNDERLI W, MEYLAN P, YERLY S, PERRIN L, LETOVANEC I, NICOD L, TAPPAREL C, SOCCAL PM Pretransplantation CMV-specific T cells protect recipients of T-cell-depleted grafts against CMV-related complications BLOOD 2006 vol. 07(1) pp. 389-396 CHALANDON Y. ET AL. A prospective hospital-based study of the clinical impact of non-severe acute respiratory syndrome (non-SARS)-related human coronavirus infection CLINICAL INFECTIOUS DISEASES 2006 vol. 43 pp. 1009-1015 GARBINO J, CRESPO S, AUBERT JD, ROCHAT T, NINET B, DEFFERNEZ C, WUNDERLI W, PACHE JC, SOCCAL PM, KAISER L Influenza will not miss opportunities CLINICAL INFECTIOUS DISEASES 2006 vol. 43 pp. 1562-1564 KAISER L Analysis of factors that contribute to treatment failure in patients with community-acquired pneumonia EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES 2006 vol. 25 pp. 159-166 GENNE D, SOMMER R, KAISER L, SAAIDIA A, PASCHE A, UNGER P, LEW D HIV and solid organ transplantation: The Swiss experience SWISS MEDICAL WEEKLY 2006 vol. 136 pp. 194-196 MULLER NJ, HIRSCHEL B, FURRER H, KAISER L, CAVASSINI M, FELLAY J, CHAVE JP, WUTHRICH RP, WEBER M, MULLHAUPT B, CANDINAS D, REICHEN F, GIOSTRA E, MENTHA G, HALKIC N, HIRSCH HH, WEBER R Portal vein thrombosis following a primary cytomegalovirus infection in an immunocompetent adult THROMBOSIS AND HAEMOSTASIS 2006 vol. 95 pp. 199-201 GUEDDI S, RIGHINI M, MEZGER N, MORARD I, KAISER L, GIOSTRA E, BOUNAMEAUX H, ANGELILLO-SCHERRER A Detection and quantification of nucleic acids in infections diseases: utility and limitations REVUE MÉDICALE SUISSE 2005 vol. 1(13) pp. 887-890 YERLY S, KAISER L, NINET B Consequences of an unsufficient range of immunity in "pediatric" infectious diseases--example with measles THERAPEUTISCHE UMSCHAU : MONATSSCHRIFT FUER PRAKTISCHE MEDIZIN = REVUE THERAPEUTIQUE : REVUE MENSUELLE DE MEDECINE PRATIQUE 2005 vol. 62(10) pp. 679-684 UCKAY ILKER, SAX HUGO, HUGONNET STEPHANE, ARAMBURU C, BESSIRE N, RUTSCHMANN OLIVIER, KAISER LAURENT, GERVAIX ALAIN, SUDRE PHILIPPE, SIEGRIST CLAIRE-ANNE, PITTET DIDIER Impact of oseltamivir treatment on influenza-related lower respiratory tract complications and hospitalisations. ARCHIVES OF INTERNAL MEDICINE 2003 vol. 163 pp. 1667-1672 KAISER L, WAT CYNTHIA, MILLS TRACY, MAHONEY PAUL, WARD PENELOPE, HAYDEN FREDERICK Monitoring of cytomegalovirus infection in solid-organ transplant recipients by an ultrasensitive plasma PCR assay JOURNAL OF CLINICAL MICROBIOLOGY 2003 vol. 41 pp. 3757-3764 HADAYA K, WUNDERLI W, DEFFERNEZ C, MARTIN PY, MENTHA G, BINET I, PERRIN L, KAISER L Improved monitoring of cytomegalovirus infection after allogeneic hematopoietic stem cell transplantation by an ultrasensitive plasma DNA PCR assay JOURNAL OF CLINICAL MICROBIOLOGY 2002 vol. 40 pp. 4251-4255 KAISER L, PERRIN L, CHAPUIS B, HADAYA K, KOLAROVA L, DEFFERNEZ C, HUGUET S, HELG C, WUNDERLI W Research's domains TRANSPLANTATION CLINICAL VIROLOGY INFLUENZA SUPERVISION RHINOVIRUS RESPIRATORY VIRUSES