DATABASE-RESEARCH | GROUP OF CLINICAL BIOLOGY RESEARCH | ||||||
Catherine PASTOR | Head of group CV | Research subject | Members of the group |
Links about the group
Dr. C. PASTOR HUG/ Dpt Radiologie Serv RadioDiag. Radio Interv Rue Gabrielle-Perret-Gentil 4 1211 Genève Suisse Catherine.Pastor@hcuge.ch Tel.: +41 22 382 38 36 Fax: +41 22 347 59 79 Comments Pages updated the 17.11.2015 |
Reseach's subject
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Group's publications
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Research's domains
Regulation of hepatic blood flow and functions
Our research is focused on the regulation of hepatic blood flow and functions in various experimental models, including biliary cirrhosis in rats and liver transplantation in pigs. Our main interests
are the vascular reactivity and the regulation of the endothelial NO synthase. The laboratory also investigates the physiopathology of acute pancreatitis and pancreatitis-associated lung injury.
Finally, we recently studied the transport mechanisms of Magnetic Resonance Imaging (MRI) contrast agents. This new subject will be extensively developed in the following years.
Group's publications Hepatopulmonary syndrome GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE 2009 vol. 33(6-7) pp. 565-579 THEVENOT T AND AL. Hepatic regeneration is decreased in a rat model of sinusoidal obstruction syndrome. JOURNAL OF SURGICAL ONCOLOGY 2009 vol. 99(7) pp. 439-446 SCHIFFER E, FROSSARD JL, RUBBIA-BRANDT L, MENTHA G, PASTOR CM Experimental evidence of obesity as a risk factor for severe acute pancreatitis. WORLD JOURNAL OF GASTROENTEROLOGY 2009 vol. 15(42) pp. 5260-5265 FROSSARD JL, LESCUYER P, PASTOR CM Laparoscopic colon surgery: unreliability of end-tidal CO2 monitoring. ACTA ANAESTHESIOLOGICA SCANDINAVICA 2008 vol. 52(5) pp. 700-707 KLOPFENSTEIN CE, SCHIFFER E, PASTOR CM, BEAUSSIER M, FRANCIS K, SORAVIA C, HERRMANN FR Acute pancreatitis. LANCET 2008 vol. 371(9607) pp. 143-152 FROSSARD JL, STEER M, PASTOR CM Proteomic profiling in an animal model of acute pancreatitis. PROTEOMICS 2008 vol. 8(17) pp. 3621-3631 FETAUD V, FROSSARD JL, FARINA A, PASTOR CM, BUHLER L, DUMONCEAU JM, HADENGUE A, HOCHSTRASSER DENIS, LESCUYER P Concomitant autoimmune and genetic pancreatitis leads to severe inflammatory conditions. WORLD JOURNAL OF GASTROENTEROLOGY 2008 vol. 14(16) pp. 2596-2598 FROSSARD JL, DUMONCEAU JM, PASTOR CATHERINE, SPAHR L, HADENGUE A Opposite regulation of endothelial NO synthase by HSP90 and caveolin in liver and lungs of rats with hepatopulmonary syndrome AMERICAN JOURNAL OF PHYSIOLOGY 2007 vol. 293(4) pp. 867-870 FROSSARD JL, SCHIFFER E, CIKIRIKCIOGLU B, BOURQUIN J, MOREL DR, PASTOR CM Improved visualization of vessels and hepatic tumors by micro-computed tomography (CT) using iodinated liposomes INVESTIGATIVE RADIOLOGY 2007 vol. 42 pp. 652-658 MONTET X, PASTOR CM, VALLEE JP, BECKER CD, GEISSBUHLER A, MOREL DR, MEDA P Model-based analysis of Gd-BOPTA-induced MR signal intensity changes in cirrhotic rat livers INVESTIGATIVE RADIOLOGY 2007 vol. 42 pp. 513-521 PLANCHAMP C, GEX-FABRY M, BECKER CD, PASTOR CM Function of both sinusoidal and canalicular transporters controls the concentration of organic anions within hepatocytes MOLECULAR PHARMACOLOGY 2007 vol. 71 pp. 1089-1097 PLANCHAMP C, HADENGUE A, STIEGER B, BOURQUIN J, VONLAUFEN A, FROSSARD JL, QUADRI R, BECKER CD, PASTOR CM Therapy insight: hepatopulmonary syndrome and orthotopic liver transplantation NATURE CLINICAL PRACTICE GASTROENTEROLOGY & HEPATOLOGY 2007 vol. 4 pp. 614-621 PASTOR CM, SCHIFFER E Hepatopulmonary syndrome increases the postoperative mortality rate following liver transplantation: a prospective study in 90 patients AMERICAN JOURNAL OF TRANSPLANTATION 2006 vol. 6(6) pp. 1430-1437 SCHIFFER E. ET AL. Time course of lung injury in rats with acute pancreatitis INTENSIVE CARE MEDICINE 2006 vol. 32(11) pp. 1872-1880 MOREL DENIS R, FROSSARD JEAN-LOUIS, CIKIRICIOGLU BANU, TAPPONNIER MAXIME, PASTOR CATHERINE M. The role of junctional adhesion molecule C (JAM-C) in acute pancreatitis JOURNAL OF PATHOLOGY 2006 vol. 209 pp. 540-548 VONLAUFEN A, AURRAND-LIONS M, PASTOR CM, LAMAGNA C, HADENGUE A, IMHOF BA, FROSSARD JL Endothelial nitric oxide synthase regulation is altered in pancreas from cirrhotic rats WORLD JOURNAL OF GASTROENTEROLOGY 2006 vol. 12 pp. 228-233 FROSSARD JL, PASTOR CM, QUADRI R, HADENGUE A, MOREI P Epidural anaesthesia restores pancreatic microcirculation and decreases the severity of acute pancreatitis WORLD JOURNAL OF GASTROENTEROLOGY 2006 vol. 12 pp. 915-920 DEMIRAG A, PASTOR CM, MOREL P, JEAN-CHRISTOPHE C, SIELENKAMPER AW, GUVENER N, MAI G, BERNEY T, FROSSARD JL, BUHLER LH Neutrophil depletion--but not prevention of Kupffer cell activation--decreases the severity of cerulein-induced acute pancreatitis WORLD JOURNAL OF GASTROENTEROLOGY 2006 vol. 12(8) pp. 1219-1224 PASTOR CATHERINE, VONLAUFEN ALAIN, GREGORI F, HADENGUE ANTOINE, MOREL PHILIPPE, FROSSARD JEAN-LOUIS Soluble CD40 ligand in prediction of acute severe pancreatitis WORLD JOURNAL OF GASTROENTEROLOGY 2006 vol. 12 pp. 1613-1616 FROSSARD JL, MOREL P, KWAK BR, PASTOR CM, BERNEY T, BUHLER L, VON LAUFEN A, DEMULDER S, MACH F Direct evidence of the temperature dependence of Gd-BOPTA transport in the intact rat liver APPLIED RADIATION AND ISOTOPES : INCLUDING DATA, INSTRUMENTATION AND METHODS FOR USE IN AGRICULTURE, INDUSTRY AND MEDICINE 2005 vol. 62 pp. 943-949 PLANCHAMP MESSEILLER CORINNE, BEYER GERD-JURGEN, SLOSMAN DANIEL, TERRIER FRANCOIS, PASTOR CATHERINE Magnetic resonance imaging with hepatospecific contrast agents in cirrhotic rat livers INVESTIGATIVE RADIOLOGY 2005 vol. 40 pp. 187-194 PLANCHAMP CAROLINE, MONTET XAVIER, FROSSARD JEAN-LOUIS, QUADRI DEFILIPPIS RAFAEL, STIEGER BRUNO, MEIER PETER, IVANCEVIC MARKO, VALLEE JEAN-PAUL, TERRIER FRANCOIS, PASTOR CATHERINE Quantification of Gd-BOPTA uptake and biliary excretion from dynamic MRI in rat livers : model validation with 153 Gd-BOPTA INVESTIGATIVE RADIOLOGY 2005 vol. 40 pp. 705-714 PLANCHAMP MESSEILLER CORINNE, PASTOR CATHERINE, BALANT LUC, BECKER CHRISTOPH, TERRIER FRANCOIS, GEX-FABRY PUN MARIANNE Tracking mesenchymal stem cells in the liver by magnetic resonance imaging JOURNAL OF HEPATOLOGY 2005 vol. 43 pp. 915-916 PASTOR CATHERINE Hsp70 does not mediate the hyperthermia-associated hyporesponsiveness to angiotensin in isolated rat portal veins LIFE SCIENCES 2005 vol. 78 pp. 41-46 FROSSARD JEAN-LOUIS, MASTRANGELO DOMINIQUE, HADENGUE ANTOINE, PASTOR CATHERINE Hollow fiber bioreactor: new development for the study of contrast agent transport into hepatocytes by magnetic resonance imaging BIOTECHNOLOGY AND BIOENGINEERING 2004 vol. 85 pp. 656-665 PLANCHAMP C, IVANCEVIC MK, PASTOR CM, VALLEE JP, POCHON S, TERRIER F, MAYER JM, REIST M Role of Toll-like receptor 4 on pancreatic and pulmonary injury in a mice model of acute pancreatitis associated with endotoxemia CRITICAL CARE MEDICINE 2004 vol. 32 pp. 1759-1763 PASTOR CM, PUGIN J, KWAK BR, CHANSON M, MACH F, HADENGUE A, FROSSARD JL Hyperthermia decreases the response to vasoconstrictor in rat portal veins EUROPEAN JOURNAL OF PHARMACOLOGY 2004 vol. 494 pp. 191-197 PASTOR CATHERINE Gd-BOPTA transport into rat hepatocytes: pharmacokinetic analysis of dynamic magnetic resonance images using a hollow-fiber bioreactor INVESTIGATIVE RADIOLOGY 2004 vol. 39 pp. 506-515 PLANCHAMP C, GEX-FABRY M, DORNIER C, QUADRI R, REIST M, IVANCEVIC MK, VALLEE JP, POCHON S, TERRIER F, BALANT L, STIEGER B, MEIER PJ, PASTOR CM Perioperative management of patients with increased risk of laparoscopy-induced hepatic hypoperfusion SWISS MEDICAL WEEKLY 2004 vol. 134 pp. 39-43 CLERGUE F, MOREL P, PASTOR CM Kinetics of gadobenate dimeglumine in isolated perfused rat liver: MR imaging evaluation RADIOLOGY 2003 vol. 229 pp. 119-125 PASTOR CM, PLANCHAMP CORINNE, POCHON SYLVIE, LORUSSO VITTORIO, MONTET X, MAYER JOACHIM, TERRIER F, VALLEE JP Effect of hyperthermic preconditioning on cold preserved rat portal veins JOURNAL OF HEPATOLOGY 2002 vol. 37 pp. 640-647 PASTOR CM, FROSSARD JL, MENTHA G, MASTRANGELO D, QUADRI R, HADENGUE A Are genetically modified mice useful for the understanding of acute pancreatitis ? FASEB JOURNAL 2001 vol. 15(6) pp. 893-897 PASTOR CM, FROSSARD JL Shear stress modulates the vascular tone in perfused livers isolated from normal rats HEPATOLOGY 2000 vol. 32 pp. 786-791 PASTOR CM, HADENGUE A Sepsis decreases the spontaneous and agonist-induced contractile activities in the rat portal vein. JOURNAL OF HEPATOLOGY 2000 vol. 33 pp. 933-940 MASTRANGELO D, FROSSARD JL, HADENGUE A, PASTOR CM Research's domains |