Radicaux libres et cellules souches embryonnaires

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Publications du groupe

NADPH Oxidase 1 Deficiency Alters Caveolin Phosphorylation and Angiotensin II-Receptor Localization in Vascular Smooth Muscle
ANTIOXIDANTS & REDOX SIGNALING
2009 vol. 11(10) pp. 2371-2384
BASSET O, DEFFERT C, FOTI M, BEDARD K, JAQUET V, OGIER-DENIS E, KRAUSE KH

NOX Enzymes in the Central Nervous System: From Signaling to Disease
ANTIOXIDANTS & REDOX SIGNALING
2009 vol. 11(10) pp. 2481-2504
SORCE S, KRAUSE KH

Small-Molecule NOX Inhibitors: ROS-Generating NADPH Oxidases as Therapeutic Targets
ANTIOXIDANTS & REDOX SIGNALING
2009 vol. 11(10) pp. 2535-2552
JAQUET V, SCAPOZZA L, CLARK RA, KRAUSE KH, LAMBETH JD

Mechanisms of Vascular Smooth Muscle NADPH Oxidase 1 (Nox1) Contribution to Injury-Induced Neointimal Formation
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
2009 vol. 29(4) pp. 480-487
LEE MY AND AL.

Involvement of NOX2 in the Development of Behavioral and Pathologic Alterations in Isolated Rats
BIOLOGICAL PSYCHIATRY
2009 vol. 66(4) pp. 384-392
SCHIAVONE S, SORCE S, DUBOIS-DAUPHIN M, JAQUET V, COLAIANNA M, ZOTTI M, CUOMO V, TRABACE L, KRAUSE KH

Distinct roles of BARD1 isoforms in mitosis: full-length BARD1 mediates Aurora B degradation, cancer-associated BARD1beta scaffolds Aurora B and BRCA2.
CANCER RESEARCH
2009 vol. 69(3) pp. 1125-1134
RYSER S, DIZIN E, JEFFORD CE, DELAVAL B, GAGOS S, CHRISTODOULIDOU A, KRAUSE KH, BIRNBAUM D, IRMINGER-FINGER I

Dissemination of intraperitoneal ovarian cancer: Discussion of mechanisms and demonstration of lymphatic spreading in ovarian cancer model
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
2009 vol. 72(1) pp. 1-9
FEKI A, BERARDI P, BELLINGAN G, MAJOR A, KRAUSE KH, PETIGNAT P, ZEHRA R, PERVAIZ S, IRMINGER-FINGER I

Three Common Polymorphisms in the CYBA Gene Form a Haplotype Associated With Decreased ROS Generation
HUMAN MUTATION
2009 vol. 30(7) pp. 1123-1133
BEDARD K, ATTAR H, BONNEFONT J, JAQUET V, BOREL C, PLASTRE O, STASIA MJ, ANTONARAKIS SE, KRAUSE KH

Does dementia predict adverse hospitalization outcomes? A prospective study in aged inpatients
INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
2009 vol. 24(3) pp. 283-291
ZEKRY D, HERRMANN FR, GRANDJEAN R, VITALE AM, DE PINHO MF, MICHEL JP, GOLD G, KRAUSE KH

Pluripotent stem cells as new drugs? The example of Parkinson's disease
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2009 vol. 381(2) pp. 113-121
PREYNAT-SEAUVE O, BURKHARD PR, VILLARD J, ZINGG W, GINOVART N, FEKI A, DUBOIS-DAUPHIN M, HURST S, MAURON A, JACONI M, KRAUSE KH

Neural progenitors derived from human embryonic stem cells are targeted by allogeneic T and natural killer cells.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
2009 vol. 13(9B) pp. 3556-3569
PREYNAT-SEAUVE O, DE RHAM C, TIREFORT D, FERRARI-LACRAZ SYLVIE, KRAUSE KH, VILLARD J

Phenazopyridine induces and synchronizes neuronal differentiation of embryonic stem cells.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
2009 vol. 13(9B) pp. 3517-3527
SUTER DM, PREYNAT-SEAUVE O, TIREFORT D, FEKI A, KRAUSE KH

Phenazopyridine induces and synchronizes neuronal differentiation of embryonic stem cells.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
2009 vol. 13(9B) pp. 3517-3527
SUTER DM, PREYNAT-SEAUVE O, TIREFORT D, FEKI A, KRAUSE KH

Editorial: Genetic mapping--the path of discovery for novel functions of the NOX NADPH oxidases.
JOURNAL OF LEUKOCYTE BIOLOGY
2009 vol. 86(3) pp. 461-463
JAQUET V, BEDARD K

A Sox1 to Pax6 Switch Drives Neuroectoderm to Radial Glia Progression During Differentiation of Mouse Embryonic Stem Cells
STEM CELLS
2009 vol. 27(1) pp. 49-58
SUTER DM, TIREFORT D, JULIEN S, KRAUSE KH

Development of Human Nervous Tissue upon Differentiation of Embryonic Stem Cells in Three-Dimensional Culture
STEM CELLS
2009 vol. 27(3) pp. 509-520
PREYNAT-SEAUVE O, SUTER DM, TIREFORT D, TURCHI L, VIROLLE T, CHNEIWEISS H, FOTI M, LOBRINUS JA, STOPPINI L, FEKI A, DUBOIS-DAUPHIN M, KRAUSE KH

Lymph node tumor metastases: more susceptible than primary tumors to CD8(+) T-cell immune destruction
TRENDS IN IMMUNOLOGY
2009 vol. 30(12) pp. 569-573
CONTASSOT E, PREYNAT-SEAUVE O, FRENCH L, HUARD B

Demented versus non-demented very old inpatients: the same comorbidities but poorer functional and nutritional status.
AGE AND AGEING
2008 vol. 37(1) pp. 83-89
ZEKRY D, HERRMANN FR, GRANDJEAN R, MEYNET MP, MICHEL JP, GOLD G, KRAUSE KH

Evolutionary forces shape the human RFPL1,2,3 genes toward a role in neocortex development.
AMERICAN JOURNAL OF HUMAN GENETICS
2008 vol. 83(2) pp. 208-218
BONNEFONT J, NIKOLAEV SI, PERRIER ARNAUD, GUO S, CARTIER L, SORCE S, LAFORGE T, AUBRY L, KHAITOVICH P, PESCHANSKI M, ANTONARAKIS SE, KRAUSE KH

NOX family NADPH oxidases in liver and in pancreatic islets: a role in the metabolic syndrome and diabetes?
BIOCHEMICAL SOCIETY TRANSACTIONS
2008 vol. 36(Pt 5) pp. 920-929
GUICHARD C, MOREAU R, PESSAYRE D, EPPERSON TK, KRAUSE KH

Regulation of NOX1 expression by GATA, HNF-1alpha, and Cdx transcription factors.
FREE RADICAL BIOLOGY AND MEDICINE
2008 vol. 44(3) pp. 430-443
VALENTE AJ, ZHOU Q, LU Z, HE W, QIANG M, MA W, LI G, WANG L, BANFI B, STEGER K, KRAUSE KH, CLARK RA, LI S

Neurotoxic activation of microglia is promoted by a nox1-dependent NADPH oxidase.
JOURNAL OF NEUROSCIENCE
2008 vol. 28(46) pp. 12039-12051
CHÉRET C, GERVAIS A, LELLI A, AMAR L, RAVASSARD P, MALLET J, CUMANO A, KRAUSE KH, MALLAT M

Branched fungal beta-glucan causes hyperinflammation and necrosis in phagocyte NADPH oxidase-deficient mice.
JOURNAL OF PATHOLOGY
2008 vol. 214(4) pp. 434-444
SCHAPPI MG, DEFFERT C, FIETTE LAURENCE, GAVAZZI G, HERRMANN F, BELLI D, KRAUSE KH

Neural commitment of embryonic stem cells: molecules, pathways and potential for cell therapy.
JOURNAL OF PATHOLOGY
2008 vol. 215(4) pp. 355-368
SUTER DAVID, KRAUSE KH

Hyperinflammation in chronic granulomatous disease and anti-inflammatory role of the phagocyte NADPH oxidase.
SEMINARS IN IMMUNOPATHOLOGY
2008 vol. 30(3) pp. 255-271
SCHAPPI MG, JAQUET V, BELLI DC, KRAUSE KH

NOX enzymes as novel targets for drug development.
SEMINARS IN IMMUNOPATHOLOGY
2008 vol. 30(3) pp. 339-363
LAMBETH JD, KRAUSE KH, CLARK RA

NOX enzymes in immuno-inflammatory pathologies.
SEMINARS IN IMMUNOPATHOLOGY
2008 vol. 30(3) pp. 193-194
KRAUSE KH, BEDARD K

The NADPH oxidase NOX2 plays a role in periodontal pathologies.
SEMINARS IN IMMUNOPATHOLOGY
2008 vol. 30(3) pp. 273-278
GIANNOPOULOU C, KRAUSE KH, MULLER F

A pure population of ectodermal cells derived from human embryonic stem cells.
STEM CELLS
2008 vol. 26(2) pp. 440-444
ABERDAM E, BARAK E, ROULEAU M, DE LAFOREST S, BERRIH-AKNIN S, SUTER DM, KRAUSE KH, AMIT M, ITSKOVITZ-ELDOR J, ABERDAM D

NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation
BIOCHEMICAL JOURNAL
2007 vol. 406 pp. 105-114
SERRANDER L, CARTIER L, BEDARD K, BANFI B, LARDY B, PLASTRE O, SIENKIEWICZ A, FORRO L, SCHLEGEL W, KRAUSE KH

NOX family NADPH oxidases: Not just in mammals
BIOCHIMIE
2007 vol. 89 pp. 1107-1112
BEDARD, K, LARDY, B, KRAUSE, KH

Extralymphatic tumors prepare draining lymph nodes to invasion via a T-cell cross-tolerance process
CANCER RESEARCH
2007 vol. 67 pp. 5009-5016
PREYNAT-SEAUVE O, CONTASSOT E, SCHULER P, PIGUET V, FRENCH LE, HUARD B

Aging: a revisited theory based on free radicals generated by NOX family NADPH oxidases
EXPERIMENTAL GERONTOLOGY
2007 vol. 42(4) pp. 256-262
KRAUSE KARL-HEINZ

NOX1 deficiency protects from aortic dissection in response to angiotensin II
HYPERTENSION
2007 vol. 50(1) pp. 189-196
GAVAZZI GAETAN, DEFFERT CHRISTINE, TROCME CANDICE, SCHÄPPI MICHELA, HERRMANN FRANÇOIS R., KRAUSE KARL-HEINZ

Expression and function of alpha-smooth muscle actin during embryonic-stem-cell-derived cardiomyocyte differentiation.
JOURNAL OF CELL SCIENCE
2007 vol. 120(Pt 2) pp. 229-238
CLEMENT S, STOUFFS M, BETTIOL ESTHER, KRAUSE KH, CHAPONNIER C, JACONI M

Branched fungal beta-glucan causes hyperinflammation and necrosis in phagocyte NADPH oxidase-deficient mice
JOURNAL OF PATHOLOGY
2007 vol. 214(4) pp. 434-444
ZEKRY D, HERRMANN F, GRANDJEAN R, MICHEL JP, GOLD G, KRAUSE KH

Melanoma-infiltrating dendritic cells induce protective antitumor responses mediated by T cells
MELANOMA RESEARCH
2007 vol. 17 pp. 169-176
PREYNAT-SEAUVE O, CONTASSOT E, SCHULER P, FRENCH LE, HUARD B

The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology
PHYSIOLOGICAL REVIEWS
2007 vol. 87(1) pp. 245-313
BEDARD K, KRAUSE KH

Genetic engineering of embryonic stem cells
SWISS MEDICAL WEEKLY
2007 vol. 155 pp. 36-38
SUTER DAVID M., DUBOIS-DAUPHIN MICHEL, KRAUSE KARL-HEINZ

Decreased blood pressure in NOX1-deficient mice
FEBS LETTERS
2006 vol. 580 pp. 497-504
GAVAZZI G, BANFI B, DEFFERT C, FIETTE L, SCHAPPI M, HERRMANN F, KRAUSE KH

Microcebus murinus: a useful primate model for human cerebral aging and Alzheimer's disease?
GENES BRAIN AND BEHAVIOR
2006 vol. 5(2) pp. 120-130
BONS N, RIEGER F, PRUDHOMME D, FISHER A, KRAUSE K.-H.

Expression and function of alpha-smooth muscle actin during embryonic-stem-cell-derived cardiomyocyte differentiation
JOURNAL OF CELL SCIENCE
2006 vol. 120(Pt 2) pp. 229-238
CLEMENT SOPHIE, STOUFFS MICHAEL, BETTIOL ESTHER, KAMPF SANDY, KRAUSE KARL-HEINZ, CHAPONNIER CHRISTINE, JACONI MARISA

Tumor-infiltrating dendritic cells are potent antigen-presenting cells able to activate T cells and mediate tumor rejection
JOURNAL OF IMMUNOLOGY
2006 vol. 176 pp. 61-67
PREYNAT-SEAUVE O, SCHULER P, CONTASSOT E, BEERMANN F, HUARD B, FRENCH LE

Pax6-induced alteration of cell fate: Shape changes, expression of neuronal a tubulin, postmitotic phenotype, and cell migration
JOURNAL OF NEUROBIOLOGY
2006 vol. 66 pp. 421-436
CARTIER L, LAFORGE T, FEKI A, ARNAUDEAU S, DUBOIS-DAUPHIN M, KRAUSE KH

Procalcitonin - You only find what you look for, and you only look for what you know - Response
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
2006 vol. 54 pp. 547-548
GAVAZZI G, HERRMANN FR, STUCKER F, GRAF JD, MICHEL JP, KRAUSE KH

Procalcitonin in older people: An unresolved problem - Response
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
2006 vol. 54 pp. 545-546
GAVAZZI G, HERRMANN FR, STUCKER F, GRAF JD, MICHEL JP, KRAUSE KH

A key role for the microglial NADPH oxidase in APP-dependent killing of neurons
NEUROBIOLOGY OF AGING
2006 vol. 27 pp. 1577-1587
QIN BIN, CARTIER L, DUBOIS-DAUPHIN M, LI B, SERRANDER L, KRAUSE KARL-HEINZ

Embryonic and adult stem cell-derived cardiomyocytes: lessons from in vitro models
REVIEWS OF PHYSIOLOGY, BIOCHEMISTRY AND PHARMACOLOGY
2006 vol. 157 pp. 1-30
BETTIOL E., CLEMENT S., KRAUSE K.-H., JACONI M.E.

Rapid generation of stable transgenic embryonic stem cell lines using modular lentivectors
STEM CELLS
2006 vol. 24(3) pp. 615-623
SUTER DAVID M, CARTIER LAETITIA, BETTIOL ESTHER, TIREFORT DIDERIK, JACONI MARISA, DUBOIS-DAUPHIN MICHEL, KRAUSE KARL-HEINZ

Genetic engineering of embryonic stem cells
SWISS MEDICAL WEEKLY
2006 vol. 136 pp. 413-415
SUTER DM, DUBOIS-DAUPHIN M, KRAUSE KH

Chemokine receptors in the central nervous system: role in brain inflammation and neurodegenerative diseases
BRAIN RESEARCH BRAIN RESEARCH REVIEWS
2005 vol. 48 pp. 16-42
CARTIER LAETITIA, HARTLEY OLIVER, DUBOIS-DAUPHIN MICHEL, KRAUSE KARL-HEINZ

Expression of mRNA for ROS-generating NADPH oxidases in the aging stomach
EXPERIMENTAL GERONTOLOGY
2005 vol. pp. 353-357
SALLES N, SZANTO ILDIKO, HERMANN FRANCOIS, ARMENIAN BERJ, STUMM M, STAUFFER E, MICHEL JEAN-PIERRE, KRAUSE KARL-HEINZ

Expression of NOX1, a superoxide-generating NADPH oxidase, in colon cancer and inflammatory bowel disease.
JOURNAL OF PATHOLOGY
2005 vol. 207(2) pp. 164-176
SZANTO ILDIKO, RUBBIA BRANDT LAURA, KISS PETER, KLAUS STEGER, BANFI BOTOND, KOVARI ENIKO, HERRMANN FRANCOIS, HADENGUE ANTOINE, KRAUSE KARL-HEINZ

BARD1 induces apoptosis by catalysing phosphorylation of p53 by DNA-damage response kinase
ONCOGENE : AN INTERNATIONAL JOURNAL
2005 vol. 24(23) pp. 3726-3736
FEKI ANIS, JEFFORD C.E, BERARDI P, WU J.Y, CARTIER LAETITIA, KRAUSE KARL-HEINZ, IRMINGER-FINGER I

Aging and infectious diseases in the developing world
CLINICAL INFECTIOUS DISEASES
2004 vol. 39(1) pp. 83-91
GAVAZZI GAETAN, HERRMANN FRANCOIS, KRAUSE KARL-HEINZ

Mechanism of Ca2+ activation of the NADPH oxidase 5 (NOX5)
JOURNAL OF BIOLOGICAL CHEMISTRY
2004 vol. 279(18) pp. 18583-18591
BÁNFI B, TIRONE F, DURUSSEL I, KNISZ J, MOSKWA P, MOLNÁR GZ, KRAUSE KH, COX JA

NOX3, a superxoide-generating NADPH oxidase of the inner ear.
JOURNAL OF BIOLOGICAL CHEMISTRY
2004 vol. 29;279(44) pp. 46065-46072
BANFI B, MALGRANGE B, KNISZ J, STEGER K, DUBOIS-DAUPHIN MICHEL, KRAUSE KARL-HEINZ

Pneumonia in the very old
THE LANCET INFECTIOUS DISEASES
2004 vol. 4(2) pp. 112-124
JANSSENS JEAN-PAUL, KRAUSE KARL-HEINZ

Two novel proteins activate superoxide generation by the NADPH oxidase NOX1
JOURNAL OF BIOLOGICAL CHEMISTRY
2003 vol. 278(6) pp. 3510-3513
BANFI B, CLARK RA, STEGER K, KRAUSE KH

Chemokine-induced cell death in CCR5-expressing neuroblastoma cells
JOURNAL OF NEUROIMMUNOLOGY.
2003 vol. pp. 27-39
CARTIER L, DUBOIS-DAUPHIN M, HARTLEY O, IRMINGER-FINGER I, KRAUSE KH

The HIV-1 Nef protein and phagocyte NADPH oxidase activation
JOURNAL OF BIOLOGICAL CHEMISTRY
2002 vol. 277 pp. 42136-42143
FREDERIK VILHARDT, OLIVIER PLASTRE, MAKOTO SAWADA, KAZUO SUZUKI, WIZNEROWICZ M, KIYOKAWA E, TRONO D, KRAUSE KH

Ageing and infection
THE LANCET INFECTIOUS DISEASES
2002 vol. 2 pp. 659-666
GAVAZZI G, KRAUSE KH

A ca(2+)-activated nadph oxidase in testis, spleen, and lymph nodes
JOURNAL OF BIOLOGICAL CHEMISTRY
2001 vol. 276 pp. 37594-37601
BANFI B, MOLNAR G, MATURANA A, STEGER K, HEGEDUS B, DEMAUREX N, KRAUSE KH

Identification of BARD1 as a mediator between proapoptotic stress and p53-dependent apoptosis.
MOLECULAR CELL
2001 vol. 8 pp. 1255-1266
IRMINGER-FINGER I, LEUNG WC, LI J, DUBOIS-DAUPHIN M, HARB J, FEKI A, JEFFORD CE, SORIANO JV, JACONI M, MONTESANO R, KRAUSE KH

Bcl-2 decrease the free Ca2+ concentration within the endoplasmic reticulum
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
2000 vol. 97 pp. 5723-5728


A mammalian H+ channel, generated through alternative splicing of the NADPH oxidase homologue NOH-1
SCIENCE
2000 vol. 287 pp. 138-142


Fibronectin-binding protein acts as Staphylococcus aureus invasin via fibronectin bridging to integrin alpha5beta1
CELLULAR MICROBIOLOGY
1999 vol. 1(2) pp. 101-117
SINHA B, FRANÇOIS PP, NUESSE O, FOTI M, HARTFORD OM, VAUDAUX P, FOSTER TJ, LEW PD, HERRMANN M, KRAUSE KH

Ca2+-induced exocytosis in individual human neutrophils: high- and low-affinity granule populations and submaximal responses
EMBO JOURNAL
1998 vol. 17(5) pp. 1279-1288
NÜSSE O, SERRANDER L, LEW DP, KRAUSE KH

Electron currents generated by the human phagocyte NADPH oxidase
NATURE
1998 vol. 392 pp. 734-737
SCHRENZEL J, SERRANDER L, BANFI B, NÜSSE O, FOUYOUZI R, LEW DP, DEMAUREX N, KRAUSE KH

Calreticulin
CELL
1997 vol. 88(4) pp. 439-443
KRAUSE KH, MICHALAK M

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Domaines de recherche