C. PICHARD - Y. DUPERTUIS  CV du Chef de Groupe  Composition du Groupe

  Coordonnées du groupe

Dr. Cl. PICHARD
HUG/Spécialités de Médecine
Serv Endo. Diabet. Nutrit.
Rue Gabrielle-Perret-Gentil 4
1211 Genève 14
Suisse

secretariat.nutrition@hcuge.ch

Tél.: 022 372 93 49
Fax: 022 372 93 63




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Pages générées le 17.11.2015
Sujet de recherche | Publications du groupe | Domaines de recherche

Nutrition

Projet 1. Évaluation du potentiel synergique d'une administration de pharmaconutriments avec la radio- ou chimiothérapie dans différents modèles de cancers gastrointestinaux.
Résumé : De récentes observations suggèrent que certains pharmaconutriments, tels que les acides gras polyinsaturés omega-3, pourraient sensibiliser sélectivement les tumeurs aux radiations et à certaines drogues en augmentant le stress oxydatif intratumoral, tout en diminuant la toxicité du traitement sur les muqueuses et l'épiderme par régulation négative de la cyclooxygénase II. Notre objectif est d'évaluer le potentiel individuel ou combiné de ces pharmaconutriments pour augmenter l'efficacité de la radio- ou chimiothérapie dans des modèles de cancers gastrointestinaux.

Projet 2. Programme éducatif basé sur un apprentissage « on line » continuellement mise-à-jour de la Nutrition Clinique.
Résumé : Ce projet fait partie intégrante du programme Leonardo Da Vinci de l'Union européenne.

Projet 3. Étude de la composition corporelle dans le cadre de l'évaluation nutritionnelle.
Résumé : Mise en place de méthodes d'évaluation et de valeurs de référence pour les masses maigre et grasse ainsi que la distribution de l'eau chez le sujet sain et dans différentes pathologies.

Projet 4. Evaluation de l'effet d'une manipulation anabolique sur l'état nutritionnel de patients avec insuffisance respiratoire chronique.
Résumé : L'impact de nutriments, d'hormones (testostérone) et/ou une activité physique sur l'état nutritionnel est évalué à partir de paramètres biologiques et physiques (composition corporelle).

Projet 5. Stabilité des micronutriments et pharmaco-économie en nutrition parentérale totale.
Résumé : Les facteurs limitants l'utilisation de poches de nutrition parentérale totale prêtes à l'emploi sont le coût et la stabilité des micronutriments dans la poche. Ces facteurs sont évalués et comparés entre différents produits et matériaux.




Publications du groupe

Differential effects of free versus imposed motor activity on alcohol consumption in C57BL/6J versus DBA/2J mice.
ALCOHOL
2009 vol. 43(8) pp. 593-601
PICHARD C, GORWOOD PA, HAMON M, COHEN-SALMON C

Decreased food intake is a risk factor for mortality in hospitalised patients: the NutritionDay survey 2006.
CLINICAL NUTRITION
2009 vol. 28(5) pp. 484-491
HIESMAYR M AND AL.

ESPEN Guidelines on Parenteral Nutrition: intensive care.
CLINICAL NUTRITION
2009 vol. 28(4) pp. 387-400
SINGER P, BERGER MM, VAN DEN BERGHE G, BIOLO G, PHILIP CALDER P, FORBES A, GRIFFITHS R, KREYMAN G, LEVERVE X, PICHARD C

Advancing from immunonutrition to a pharmaconutrition: a gigantic challenge.
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
2009 vol. 12(4) pp. 398-403
DUPERTUIS YM, MEGUID MM, PICHARD C

Dichotomic actions of glutamine in host versus tumour: an emerging concept.
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
2009 vol. 12(4) pp. 372-377
BELABED L, DARMON P, THADIKKARAN L, DUPERTUIS YM, PICHARD C

Nutritional care: from the dark ages to the renaissance, to the age of enlightenment.
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
2009 vol. 12(4) pp. 364-365
MEGUID M, LAVIANO A, PICHARD C

Do obese patients have specific nutrition goals in cases of cancer?
JPEN . JOURNAL OF PARENTERAL AND ENTERAL NUTRITION
2009 vol. 33(4) pp. 442-443
GENTON L, PICHARD C

Neural control of the anorexia-cachexia syndrome.
AMERICAN JOURNAL OF PHYSIOLOGY. ENDOCRINOLOGY AND METABOLISM
2008 vol. 295(5) pp. 1000-1008
LAVIANO A, INUI A, MARKS DL, MEGUID MM, PICHARD C, ROSSI FANELLI F, SEELAENDER M

Clinical relevance of parenteral nutrition prescription and administration in 200 hospitalized patients: a quality control study.
CLINICAL NUTRITION
2008 vol. ;27(6) pp. 858-864
NARDO P, DUPERTUIS YM, JETZER J, KOSSOVSKI MP, DARMON P, PICHARD C

Inspired by the pioneers: the lesson of the Judy Taylor story.
CLINICAL NUTRITION
2008 vol. 27(3) pp. 319-320
LJUNGQVIST O, PICHARD C

Nutrition in care homes and home care: how to implement adequate strategies (report of the Brussels Forum (22-23 November 2007)).
CLINICAL NUTRITION
2008 vol. 27(4) pp. 481-488
ARVANITAKIS M AND AL.

Oral nutritional supplements and taste preferences: 545 days of clinical testing in malnourished in-patients.
CLINICAL NUTRITION
2008 vol. 27(4) pp. 660-665
DARMON P, KARSEGARD LV, NARDO P, DUPERTUIS YM, PICHARD C

Prognostic impact of disease-related malnutrition.
CLINICAL NUTRITION
2008 vol. 27(1) pp. 5-15
NORMAN K, PICHARD C, LOCHS H, PIRLICH M

Economic impact and quality of life as endpoints of nutritional therapy.
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
2008 vol. ;11(4) pp. 452-458
DARMON P, LOCHS H, PICHARD C

Of autoantibodies and single nucleotide polymorphisms: a brave new world?
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
2008 vol. 11(4) pp. 398-399
PICHARD C, LAVIANO A, MEGUID MM

Enteral vs. parenteral nutrition for the critically ill patient: a combined support should be preferred.
CURRENT OPINION IN CRITICAL CARE
2008 vol. 14(4) pp. 408-414
HEIDEGGER CLAUDIA, DARMON P, PICHARD C

Injury stimulates an innate respiratory immunoglobulin a immune response in humans.
JOURNAL OF TRAUMA
2008 vol. 64(2) pp. 316-323
KUDSK KA, HERMSEN JL, GENTON L, FAUCHER L, GOMEZ FE

Comparison of equations for estimating resting metabolic rate in healthy subjects over 70 years of age
CLINICAL NUTRITION
2007 vol. 26 pp. 498-505
MELZER K, KARSEGARD WL, GENTON L, KOSSOVSKY MP, KAYSER B, PICHARD C

New legal regulations for clinical trials: An opportunity for the future of Clinical Nutrition research
CLINICAL NUTRITION
2007 vol. 26 pp. 510-513
DEUTZ NEP, KOLETZKO B, PICHARD C

Nutritional intervention and quality of life in adult oncology patients
CLINICAL NUTRITION
2007 vol. 26 pp. 289-301
MARIN CARO MM, LAVIANO A, PICHARD C

Colon cancer therapy: new perspectives of nutritional manipulations using polyunsaturated fatty acids
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
2007 vol. 10(4) pp. 427-432
DUPERTUIS YM, MEGUID MM, PICHARD C

mpact of nutrition on quality of life during cancer
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
2007 vol. 10(4) pp. 480-487
MARÍN CARO MM, LAVIANO A, PICHARD C

Is it now time to promote mixed enteral and parenteral nutrition for the critically ill patient?
INTENSIVE CARE MEDICINE
2007 vol. 33 pp. 963-969
HEIDEGGER CP, ROMAND JA, TREGGIARI MM, PICHARD C

Relationship between nutritional intervention and quality of life in cancer patients
NUTRICION HOSPITALARIA : ORGANO OFICIAL DE LA SOCIEDAD ESPANOLA DE NUTRICION PARENTERAL Y ENTERAL
2007 vol. 22(3) pp. 337-350
CARO MM, LAVIANO A, PICHARD C, CANDELA CG

Effect of an immunonutrient mix on human colorectal adenocarcinoma cell growth and viability
NUTRITION
2007 vol. 23 pp. 672-680
DUPERTUIS YM, BENAIS-PONT G, BUCHEGGER F, PICHARD C

Overweight and obesity in a Swiss city: 10-year trends
PUBLIC HEALTH NUTRITION
2007 vol. 10 pp. 914-919
KYLE UG, KOSSOVSKY MP, GENTON L, PICHARD C

A 3-year longitudinal study on body composition changes in the elderly: Role of physical exercise
CLINICAL NUTRITION
2006 vol. 25 pp. 573-580
RAGUSO CA, KYLE U, KOSSOVSKY MP, ROYNETTE C, PAOLONI-GIACOBINO A, HANS D, GENTON L, PICHARD C

Comparison of body weight and composition measured by two different dual energy X-ray absorptiometry devices and three acquisition modes in obese women
CLINICAL NUTRITION
2006 vol. 25 pp. 428-437
GENTON L, KARSEGARD VL, ZAWADYNSKI S, KYLE UG, PICHARD C, GOLAY A, HANS DB

Comparison of tools for nutritional assessment and screening at hospital admission: A population study
CLINICAL NUTRITION
2006 vol. 25 pp. 409-417
KYLE UG, KOSSOVSKY MP, KARSEGARD VL, PICHARD C

ESPEN guidelines on enteral nutrition: Intensive care
CLINICAL NUTRITION
2006 vol. 25 pp. 210-223
KREYMANN KG, BERGER MM, DEUTZ NEP, HIESMAYR M, NITENBERG G, VAN DEN BERGHE G, WERNERMAN J, EBNER C, HARTL W, HEYMANN C, SPIES C, JOLLIET P, KAZANDJIEV G

Evidence supports nutritional support
CLINICAL NUTRITION
2006 vol. 25(2) pp. 177-179
LOCHS H, PICHARD C, ALLISON SP

Hospitalized mechanically ventilated patients are at higher risk of enteral underfeeding than non-ventilated patients
CLINICAL NUTRITION
2006 vol. 25 pp. 727-735
KYLE UG, GENTON L, HEIDEGGER CP, MAISONNEUVE N, KARSEGARD VL, HUBER O, MENSI N, ROMAND JA, JOLLIET P, PICHARD C

Introductory to the ESPEN guidelines on enteral nutrition: Terminology, definitions and general topics
CLINICAL NUTRITION
2006 vol. 25 pp. 180-186
LOCHS H, ALLISON SP, MEIER R, PIRLICH M, KONDRUP J, SCHNEIDER S, VAN DEN BERGHE G, PICHARD C

Did it all start with Delilah?
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
2006 vol. 9 pp. 386-387
MEGUID MM, PICHARD C

Ergonomic and economic aspects of total parenteral nutrition
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
2006 vol. 9 pp. 149-154
GENTON L, MUHLEBACH S, DUPERTUIS YM, PICHARD C

The Dutch Famine of 1944-1945: a pathophysiological model of long-term consequences of wasting disease
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
2006 vol. 9 pp. 388-394
KYLE UG, PICHARD C

Eight-year longitudinal changes in body composition in healthy Swiss adults
JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION
2006 vol. 25(6) pp. 493-501
KYLE URSULA G, MELZER KATARINA, KAYSER BENGT, PICARD-KOSSOVSKY MICHEL, GREMION GERALD, PICHARD CLAUDE

Longitudinal study of body composition changes associated with weight change and physical activity
NUTRITION
2006 vol. 22 pp. 1103-1111
KYLE UG, ZHANG FF, MORABIA A, PICHARD C

omega-3 Polyunsaturated fatty acids and ionizing radiation: combined cytotoxicity on human colorectal. adenocarcinoma cells
NUTRITION
2006 vol. 22 pp. 931-939
BENAIS-PONT G, DUPERTUIS YM, KOSSOVSKY MP, NOUET P, ALLAL AS, BUCHEGGER F, PICHARD C

Body composition in patients with chronic hypercapnic respiratory failure
RESPIRATORY MEDICINE
2006 vol. 100 pp. 244-252
KYLE UG, JANSSENS JP, ROCHAT T, RAGUSO CA, PICHARD C

Diet and ageing: critical influence of genetype and gene expression profile.
NUTRITION RESEARCH
2003 vol. 23 pp. 1727-1738
PAOLONI GIACOBINO A, PICHARD C


Domaines de recherche