Welcome in the research database

Outcome & Quality

Current domains of interest

. Outcome - Quality of life of patients after an ICU stay (study terminated - manuscript) : the outcome of ICU patients are still under investigated. Such knowledge is essential for better care of the patients.

. Quality - Incidents in ICU (ongoing): studies are issued from problems related to incidents spontaneously declared in ICU

- Stress and burnout in ICU (ongoing): the ICU personal are particularly prone to burnout because of the stressful environment and special care of the patients and families. This problematic is investigated in order to establish future solutions.

. Ethics - Informed consent in research (study terminated - manuscript) : informed consent is a key element in clinical research. The group investigates the special features linked to the procurement of informed consent in the special environment of ICU.

- Advance directives and health care surrogate in patients undergoing a major cardiovascular surgery (ongoing): this is a major study sustained by the Swiss National Foundation of Research (FNRS) that investigates the reasons of interfering with the constitution of advance directives for individuals. The research project includes 3 sections: the patient, the family member and the physician.

Present composition

Dr. P.Merlani - médecin-adjoint agrégé aux SI
Mme F.Gigon - assistante de recherche
Mme AL Blanchard-Courtois - research nurse
Mme F.Scherer - assistante de recherche

The group welcomes exchanges program for foreign students for research (IFMSA)

Group's publications

"Heparinization" and hyperfibrinogenolysis by wasp sting.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
2009 vol. 27(9) pp. 1176-1176
LOMBARDINI C, HELIA RE, BOEHLEN F, MERLANI P

Prevalence and Factors of Intensive Care Unit Conflicts The Conflicus Study
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2009 vol. 180(9) pp. 853-860
AZOULAY E. AND AL.

Who should consent for research in adult intensive care? Preferences of patients and their relatives: a pilot study
JOURNAL OF MEDICAL ETHICS
2009 vol. 35(11) pp. 709-712
CHENAUD C, MERLANI P, VERDON M, RICOU B

Relieving suffering or intentionally hastening death: where do you draw the line?
CRITICAL CARE MEDICINE
2008 vol. 36(1) pp. 8-13
SPRUNG CL AND AL.

What limits for acute care in the elderly?
CURRENT OPINION IN ANAESTHESIOLOGY
2008 vol. 21(3) pp. 380-385
RICOU B, MERLANI P

Delayed matrix metalloproteinase inhibition reduces intracerebral hemorrhage after embolic stroke in rats.
EXPERIMENTAL NEUROLOGY
2008 vol. 213(1) pp. 196-201
COPIN JC, MERLANI P, SUGAWARA T, CHAN PH, GASCHE Y

Burnout in a surgical ICU team.
INTENSIVE CARE MEDICINE
2008 vol. 34(1) pp. 152-156
VERDON M, MERLANI P, PERNEGER T, RICOU B

From the ICU to the ward: cross-checking of the physician's transfer report by intensive care nurses.
INTENSIVE CARE MEDICINE
2008 vol. 34(11) pp. 2054-2061
PERREN A, CONTE P, DE BITONTI N, LIMONI C, MERLANI P

Reasons, considerations, difficulties and documentation of end-of-life decisions in European intensive care units: the ETHICUS Study.
INTENSIVE CARE MEDICINE
2008 vol. 34(2) pp. 271-277
SPRUNG CL AND AL.

Long-term outcome of elderly patients requiring intensive care admission for abdominal pathologies: survival and quality of life
ACTA ANAESTHESIOLOGICA SCANDINAVICA
2007 vol. 51 pp. 530-537
MERLANI P, CHENAUD C, MARIOTTI N, RICOU B

Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
2007 vol. 51 pp. 1341-1350
REINHARDT, A, KOHLER, T, WOOD, P, ROHNER, P, DUMAS, JL, RICOU, B, VAN DELDEN, C

Research in critically ill patients: standards of informed consent
CRITICAL CARE
2007 vol. 11 pp. 110-110
CHENAUD C, MERLANI P, RICOU B

Plethysmographic dynamic indices predict fluid responsiveness in septic ventilated patients
INTENSIVE CARE MEDICINE
2007 vol. 33(6) pp. 993-999
FEISSEL M, TEBOUL JL, MERLANI P, BADIE J, FALLER JP, BENDJELID K

The importance of religious affiliation and culture on end-of-life decisions in European intensive care units
INTENSIVE CARE MEDICINE
2007 vol. 33 pp. 1732-1739
SPRUNG CL, MAIA P, BULOW HH, RICOU B, ARMAGANIDIS A, BARAS M, WENNBERG E, REINHART K, COHEN SL, FRIES D, NAKOS G, THIJS LG

Is throat screening necessary to detect methicillin-resistant Staphylococcus aureus colonization in patients upon admission to an intensive care unit?
JOURNAL OF CLINICAL MICROBIOLOGY
2007 vol. 45(3) pp. 1072-1073
HARBARTH S., SCHRENZEL J., RENZI G., AKAKPO C., RICOU B.

Interest of psychiatric guidelines in managing agitation in intensive care
REVUE MÉDICALE SUISSE
2007 vol. 3(98) pp. 414-419
LAZIGNAC CORALIE, RICOU B, DAN L, VIRGILLITO S, ADAM E, SEYEDI M, CICOTTI ANDREI NICOLAE, AZI A, DAMSA CRISTIAN

Evaluation of rapid screening and pre-emptive contact isolation for detecting and controlling methicillin-resistant Staphylococcus aureus in critical care: an interventional cohort study
CRITICAL CARE
2006 vol. 10 pp. 0-0
HARBARTH S, MASUET-AUMATELL C, SCHRENZEL J, FRANCOIS P, AKAKPO C, RENZI G, PUGIN J, RICOU B, PITTET D

Informed consent for research obtained during the intensive care unit stay.
CRITICAL CARE
2006 vol. 10(6) pp. 170-170
CHENAUD C, MERLANI P, LUYASU S, RICOU B

Serum lipids or apolipoprotein A-I and disease severity of meningococcal sepsis
CRITICAL CARE MEDICINE
2006 vol. 34 pp. 270-271
CHENAUD C, MERLANI PG, BANDSHAPP O, RICOU B

Informed consent for research in ICU obtained before ICU admission
INTENSIVE CARE MEDICINE
2006 vol. 32 pp. 439-444
CHENAUD C, MERLANI P, RICOU B

Point of care management of heparin administration after heart surgery - A randomized, controlled trial
INTENSIVE CARE MEDICINE
2006 vol. 32 pp. 1357-1364
MERLANI PG, CHENAUD C, COTTINI S, REBER G, GARNERIN P, DE MOERLOOSE P, RICOU B

Risk factors for reperfusion injury after lung transplantation
INTENSIVE CARE MEDICINE
2006 vol. 32 pp. 557-563
COTTINI SR, LERCH N, DE PERROT M, TREGGIARI MM, SPILIOPOULOS A, NICOD L, RICOU B

Quelle est la qualité de vie des personnes après un séjour aux soins intensifs
REVUE MÉDICALE SUISSE
2006 vol. 2(91) pp. 2845-2849
CHENAUD C., RICOU B., MERLANI P.

Anti-inflammatory response after infusion of p55 soluble tumor necrosis factor receptor fusion protein for severe sepsis
EUROPEAN CYTOKINE NETWORK : THE OFFICIAL JOURNAL OF THE EUROPEAN CYTOKINE SOCIETY
2003 vol. 14 pp. 15-19
BUTTY VL, ROUX-LOMBARD P, GARBINO J, DAYER JM, RICOU B

End-of-life practices in European intensive care units. The Ethicus study
JAMA
2003 vol. 290 pp. 790-797
SPRUNG CL, COHEN SL, SJOKVIST P, BARAS M, BULOW HH, HOVILEHTO S, LEDOUX D, LIPPERT A, MAIA P, PHELAN D, RICOU B, SCHOBERSBERGER W, WENNBERG E, WOODCOCK T

Tumor necrosis factor-alpha and angiostatin are mediators of endothelial cytotoxicity in bronchoalveolar lavages of patients with acute respiratory distress syndrome
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2002 vol. 166 pp. 651-656
J. HAMACHER, R. LUCAS, H.R. LIJNEN, S. BUSCHKE, DUNANT Y, A. WENDEL, G.E. GRAU, SUTER PM, RICOU B

Epidemiology and prognostic determinants of bloodstream infections in surgical intensive care
ARCHIVES OF SURGERY (DES 1960)
2002 vol. 137 pp. 1353-1359
HARBARTH S, FERRIÈRE K, HUGONNET S, RICOU B, SUTER PM, PITTET D

Quality improvement report: Linking guideline to regular feedback to increase appropriate requests for clinical tests: blood gas analysis in intensive care.
BRITISH MEDICAL JOURNAL
2001 vol. 323 pp. 620-624
MERLANI PAOLO, GARNERIN PHILIPPE, DIBY M, FERRING M, RICOU BARA

Point of care and central laboratory determinations of the aPTT are not interchangeable in surgical intensive care patients
CANADIAN JOURNAL OF ANAESTHESIA-JOURNAL CANADIEN D ANESTHESIE
2001 vol. 48 pp. 1155-1160
FERRING M, REBER G, DE MOERLOOSE P, MERLANI P, DIBY M, RICOU B

Research's domains




DATABASE-RESEARCH	GROUP OF CLINICAL PATIENT RESEARCH

Bara RICOU	Head of group CV	Research subject	Members of the group


	Links about the group Prof. Bara RICOU HUG/ Dpt APSI Serv Soins Intensifs Rue Gabrielle-Perret-Gentil 4 1211 Genève 4 bara.ricou@hcuge.ch Tel.: +41 22 372 74 73 Fax: + 41 22 382 74 70 Comments Pages updated the 17.11.2015		Reseach's subject \| Group's publications \| Research's domains Outcome & Quality Current domains of interest . Outcome - Quality of life of patients after an ICU stay (study terminated - manuscript) : the outcome of ICU patients are still under investigated. Such knowledge is essential for better care of the patients. . Quality - Incidents in ICU (ongoing): studies are issued from problems related to incidents spontaneously declared in ICU - Stress and burnout in ICU (ongoing): the ICU personal are particularly prone to burnout because of the stressful environment and special care of the patients and families. This problematic is investigated in order to establish future solutions. . Ethics - Informed consent in research (study terminated - manuscript) : informed consent is a key element in clinical research. The group investigates the special features linked to the procurement of informed consent in the special environment of ICU. - Advance directives and health care surrogate in patients undergoing a major cardiovascular surgery (ongoing): this is a major study sustained by the Swiss National Foundation of Research (FNRS) that investigates the reasons of interfering with the constitution of advance directives for individuals. The research project includes 3 sections: the patient, the family member and the physician. Present composition Dr. P.Merlani - médecin-adjoint agrégé aux SI Mme F.Gigon - assistante de recherche Mme AL Blanchard-Courtois - research nurse Mme F.Scherer - assistante de recherche The group welcomes exchanges program for foreign students for research (IFMSA) Group's publications "Heparinization" and hyperfibrinogenolysis by wasp sting. AMERICAN JOURNAL OF EMERGENCY MEDICINE 2009 vol. 27(9) pp. 1176-1176 LOMBARDINI C, HELIA RE, BOEHLEN F, MERLANI P Prevalence and Factors of Intensive Care Unit Conflicts The Conflicus Study AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 2009 vol. 180(9) pp. 853-860 AZOULAY E. AND AL. Who should consent for research in adult intensive care? Preferences of patients and their relatives: a pilot study JOURNAL OF MEDICAL ETHICS 2009 vol. 35(11) pp. 709-712 CHENAUD C, MERLANI P, VERDON M, RICOU B Relieving suffering or intentionally hastening death: where do you draw the line? CRITICAL CARE MEDICINE 2008 vol. 36(1) pp. 8-13 SPRUNG CL AND AL. What limits for acute care in the elderly? CURRENT OPINION IN ANAESTHESIOLOGY 2008 vol. 21(3) pp. 380-385 RICOU B, MERLANI P Delayed matrix metalloproteinase inhibition reduces intracerebral hemorrhage after embolic stroke in rats. EXPERIMENTAL NEUROLOGY 2008 vol. 213(1) pp. 196-201 COPIN JC, MERLANI P, SUGAWARA T, CHAN PH, GASCHE Y Burnout in a surgical ICU team. INTENSIVE CARE MEDICINE 2008 vol. 34(1) pp. 152-156 VERDON M, MERLANI P, PERNEGER T, RICOU B From the ICU to the ward: cross-checking of the physician's transfer report by intensive care nurses. INTENSIVE CARE MEDICINE 2008 vol. 34(11) pp. 2054-2061 PERREN A, CONTE P, DE BITONTI N, LIMONI C, MERLANI P Reasons, considerations, difficulties and documentation of end-of-life decisions in European intensive care units: the ETHICUS Study. INTENSIVE CARE MEDICINE 2008 vol. 34(2) pp. 271-277 SPRUNG CL AND AL. Long-term outcome of elderly patients requiring intensive care admission for abdominal pathologies: survival and quality of life ACTA ANAESTHESIOLOGICA SCANDINAVICA 2007 vol. 51 pp. 530-537 MERLANI P, CHENAUD C, MARIOTTI N, RICOU B Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 2007 vol. 51 pp. 1341-1350 REINHARDT, A, KOHLER, T, WOOD, P, ROHNER, P, DUMAS, JL, RICOU, B, VAN DELDEN, C Research in critically ill patients: standards of informed consent CRITICAL CARE 2007 vol. 11 pp. 110-110 CHENAUD C, MERLANI P, RICOU B Plethysmographic dynamic indices predict fluid responsiveness in septic ventilated patients INTENSIVE CARE MEDICINE 2007 vol. 33(6) pp. 993-999 FEISSEL M, TEBOUL JL, MERLANI P, BADIE J, FALLER JP, BENDJELID K The importance of religious affiliation and culture on end-of-life decisions in European intensive care units INTENSIVE CARE MEDICINE 2007 vol. 33 pp. 1732-1739 SPRUNG CL, MAIA P, BULOW HH, RICOU B, ARMAGANIDIS A, BARAS M, WENNBERG E, REINHART K, COHEN SL, FRIES D, NAKOS G, THIJS LG Is throat screening necessary to detect methicillin-resistant Staphylococcus aureus colonization in patients upon admission to an intensive care unit? JOURNAL OF CLINICAL MICROBIOLOGY 2007 vol. 45(3) pp. 1072-1073 HARBARTH S., SCHRENZEL J., RENZI G., AKAKPO C., RICOU B. Interest of psychiatric guidelines in managing agitation in intensive care REVUE MÉDICALE SUISSE 2007 vol. 3(98) pp. 414-419 LAZIGNAC CORALIE, RICOU B, DAN L, VIRGILLITO S, ADAM E, SEYEDI M, CICOTTI ANDREI NICOLAE, AZI A, DAMSA CRISTIAN Evaluation of rapid screening and pre-emptive contact isolation for detecting and controlling methicillin-resistant Staphylococcus aureus in critical care: an interventional cohort study CRITICAL CARE 2006 vol. 10 pp. 0-0 HARBARTH S, MASUET-AUMATELL C, SCHRENZEL J, FRANCOIS P, AKAKPO C, RENZI G, PUGIN J, RICOU B, PITTET D Informed consent for research obtained during the intensive care unit stay. CRITICAL CARE 2006 vol. 10(6) pp. 170-170 CHENAUD C, MERLANI P, LUYASU S, RICOU B Serum lipids or apolipoprotein A-I and disease severity of meningococcal sepsis CRITICAL CARE MEDICINE 2006 vol. 34 pp. 270-271 CHENAUD C, MERLANI PG, BANDSHAPP O, RICOU B Informed consent for research in ICU obtained before ICU admission INTENSIVE CARE MEDICINE 2006 vol. 32 pp. 439-444 CHENAUD C, MERLANI P, RICOU B Point of care management of heparin administration after heart surgery - A randomized, controlled trial INTENSIVE CARE MEDICINE 2006 vol. 32 pp. 1357-1364 MERLANI PG, CHENAUD C, COTTINI S, REBER G, GARNERIN P, DE MOERLOOSE P, RICOU B Risk factors for reperfusion injury after lung transplantation INTENSIVE CARE MEDICINE 2006 vol. 32 pp. 557-563 COTTINI SR, LERCH N, DE PERROT M, TREGGIARI MM, SPILIOPOULOS A, NICOD L, RICOU B Quelle est la qualité de vie des personnes après un séjour aux soins intensifs REVUE MÉDICALE SUISSE 2006 vol. 2(91) pp. 2845-2849 CHENAUD C., RICOU B., MERLANI P. Anti-inflammatory response after infusion of p55 soluble tumor necrosis factor receptor fusion protein for severe sepsis EUROPEAN CYTOKINE NETWORK : THE OFFICIAL JOURNAL OF THE EUROPEAN CYTOKINE SOCIETY 2003 vol. 14 pp. 15-19 BUTTY VL, ROUX-LOMBARD P, GARBINO J, DAYER JM, RICOU B End-of-life practices in European intensive care units. The Ethicus study JAMA 2003 vol. 290 pp. 790-797 SPRUNG CL, COHEN SL, SJOKVIST P, BARAS M, BULOW HH, HOVILEHTO S, LEDOUX D, LIPPERT A, MAIA P, PHELAN D, RICOU B, SCHOBERSBERGER W, WENNBERG E, WOODCOCK T Tumor necrosis factor-alpha and angiostatin are mediators of endothelial cytotoxicity in bronchoalveolar lavages of patients with acute respiratory distress syndrome AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 2002 vol. 166 pp. 651-656 J. HAMACHER, R. LUCAS, H.R. LIJNEN, S. BUSCHKE, DUNANT Y, A. WENDEL, G.E. GRAU, SUTER PM, RICOU B Epidemiology and prognostic determinants of bloodstream infections in surgical intensive care ARCHIVES OF SURGERY (DES 1960) 2002 vol. 137 pp. 1353-1359 HARBARTH S, FERRIÈRE K, HUGONNET S, RICOU B, SUTER PM, PITTET D Quality improvement report: Linking guideline to regular feedback to increase appropriate requests for clinical tests: blood gas analysis in intensive care. BRITISH MEDICAL JOURNAL 2001 vol. 323 pp. 620-624 MERLANI PAOLO, GARNERIN PHILIPPE, DIBY M, FERRING M, RICOU BARA Point of care and central laboratory determinations of the aPTT are not interchangeable in surgical intensive care patients CANADIAN JOURNAL OF ANAESTHESIA-JOURNAL CANADIEN D ANESTHESIE 2001 vol. 48 pp. 1155-1160 FERRING M, REBER G, DE MOERLOOSE P, MERLANI P, DIBY M, RICOU B Research's domains