Panteleimon GIANNAKOPOULOS  Head of group CV  Members of the group

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Pr. P. GIANNAKOPOULOS
HUG/ Dpt Psychiatrie
Belle-Idée
Ch. du Petit-Bel-Air 2
1225 Chêne-Bourg
Suisse

Panteleimon.Giannakopoulos@hcuge.ch

Tel.: 022/305.50.01
Fax: 022/305.50.44




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Pages updated the 17.11.2015
Reseach's subject | Group's publications | Research's domains

Patient-oriented research and Translational research

Patient-oriented research
Identification of EEG markers of cognitive decline in mild cognitive impairment
Identification of biological and neuropsychological markers of cognitive decline in elderly patients with late-onset depression and bipolar disorders
Cognitive impact of vascular lesions in brain aging

Translational research
Stereological assessment of AD-related lesions, neuronal and synaptic loss and establishemen tof clinicopathological correlations in the oldest-old
Use of recombinant clusterin to prevent ischemic damage in organotypic cultures and after middle cerebral artery occlusion




Group's publications

Longitudinal assessment of psychotherapeutic day hospital treatment for neuropsychiatric symptoms in dementia.
AGING & MENTAL HEALTH
2009 vol. 13(1) pp. 92-98
WEBER K, MEILER-MITITELU C, HERRMANN FR, DELALOYE C, GIANNAKOPOULOS P, CANUTO A

Neuroanatomical and Neuropsychological Features of Euthymic Patients with Bipolar Disorder
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY
2009 vol. 17(12) pp. 1012-1021
DELALOYE C AND AL.

Personality Traits Influence Clinical Outcome in Day Hospital-Treated Elderly Depressed Patients
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY
2009 vol. 17(4) pp. 335-343
CANUTO A, GIANNAKOPOULOS P, MEILER-MITITELU C, DELALOYE C, HERRMANN FR, WEBER K

The contribution of aging to the understanding of the dimensionality of executive functions.
ARCHIVES OF GERONTOLOGY AND GERIATRICS
2009 vol. 49(1) pp. 51-59
DELALOYE C, MOY GUENAEL, BAUDOIS S, DE BILBAO F, DUBOIS-REMUND C, HOFER F, RAGNO-PAQUIER C, WEBER K, URBEN S, GIANNAKOPOULOS P

In vivo neuropathology of cortical changes in elderly persons with schizophrenia.
BIOLOGICAL PSYCHIATRY
2009 vol. 66(6) pp. 578-585
FRISONI GB, PRESTIA A, ADORNI A, RASSER PE, COTELLI M, SORICELLI A, BONETTI M, GEROLDI C, GIANNAKOPOULOS P, THOMPSON PM

Cognitive features in euthymic bipolar patients in old age
BIPOLAR DISORDERS
2009 vol. 11(7) pp. 735-743
DELALOYE C AND AL.

The impact of vascular burden on late-life depression.
BRAIN RESEARCH REVIEWS
2009 vol. 62(1) pp. 19-32
SANTOS M, KOVARI E, HOF PR, GOLD G, BOURAS C, GIANNAKOPOULOS P

In vivo over-expression of interleukin-10 increases resistance to focal brain ischemia in mice
JOURNAL OF NEUROCHEMISTRY
2009 vol. 110(1) pp. 12-22
DE BILBAO F, ARSENIJEVIC D, MOLL T, GARCIA-GABAY I, VALLET P, LANGHANS W, GIANNAKOPOULOS P

Assessing depression outcome in patients with moderate dementia: sensitivity of the HoNOS65+ scale.
JOURNAL OF THE NEUROLOGICAL SCIENCES
2009 vol. 283(1-2) pp. 69-72
CANUTO A, RUDHARD-THOMAZIC V, HERRMANN FR, DELALOYE C, GIANNAKOPOULOS P, WEBER K

The neuroanatomical model of post-stroke depression: towards a change of focus?
JOURNAL OF THE NEUROLOGICAL SCIENCES
2009 vol. 283(1-2) pp. 158-162
SANTOS M, KOVARI E, GOLD G, BOZIKAS VP, HOF PR, BOURAS C, GIANNAKOPOULOS P

Abnormal-induced theta activity supports early directed-attention network deficits in progressive MCI.
NEUROBIOLOGY OF AGING
2009 vol. 30(9) pp. 1444-1452
DEIBER MP, IBANEZ V, MISSONNIER P, HERRMANN F, FAZIO-COSTA L, GOLD G, GIANNAKOPOULOS P

Differential impact of lacunes and microvascular lesions on poststroke depression.
STROKE
2009 vol. 40(11) pp. 3557-3562
SANTOS M, GOLD G, KOVARI E, HERRMANN FR, BOZIKAS VP, BOURAS C, GIANNAKOPOULOS P

Interhemispheric Distribution of Alzheimer Disease and Vascular Pathology in Brain Aging
STROKE
2009 vol. 40(3) pp. 983-986
GIANNAKOPOULOS P, KOVARI E, HERRMANN FR, HOF PR, BOURAS C

Assessing the role of cingulate cortex in bipolar disorder: neuropathological, structural and functional imaging data.
BRAIN RESEARCH REVIEWS
2008 vol. 59(1) pp. 9-21
FOUNTOULAKIS KN, GIANNAKOPOULOS P, KOVARI E, BOURAS C

Cognitive impairment in late-onset depression. Limited to a decrement in information processing resources?
EUROPEAN NEUROLOGY
2008 vol. 60(3) pp. 149-154
DELALOYE C AND AL.

Impact of personality on termination of short-term group psychotherapy in depressed elderly outpatients.
INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
2008 vol. 23(1) pp. 22-26
CANUTO A, MEILER-MITITELU C, HERRMANN FR, GIANNAKOPOULOS P, WEBER K

Longitudinal assessment of psychotherapeutic day hospital treatment for elderly patients with depression.
INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
2008 vol. 23(9) pp. 949-956
CANUTO A, MEILER-MITITELU C, HERRMANN FR, DELALOYE C, GIANNAKOPOULOS P, WEBER K

Clusterin increases post-ischemic damages in organotypic hippocampal slice cultures.
JOURNAL OF NEUROCHEMISTRY
2008 vol. 106(4) pp. 1791-1803
HAKKOUM D, IMHOF A, VALLET PG, BOZE H, MOULIN G, CHARNAY Y, STOPPINI L, ARONOW B, BOURAS C, GIANNAKOPOULOS P

Clinicopathologic correlates in the oldest-old: Commentary on "No disease in the brain of a 115-year-old woman".
NEUROBIOLOGY OF AGING
2008 vol. 29(8) pp. 1137-1139
GIANNAKOPOULOS P, BOURAS C, HOF PR

Clusterin expression during fetal and postnatal CNS development in mouse.
NEUROSCIENCE
2008 vol. 155(3) pp. 714-724
CHARNAY Y, IMHOF A, VALLET PG, HAKKOUM D, LATHUILIERE A, POKU N, ARONOW B, KOVARI E, BOURAS C, GIANNAKOPOULOS P

A systematic review of existing data on long-term lithium therapy: neuroprotective or neurotoxic?
THE INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY / OFFICIAL SCIENTIFIC JOURNAL OF THE COLLEGIUM INTERNATIONALE NEUROPSYCHOPHARMACOLOGICUM (CINP)
2008 vol. 11(2) pp. 269-287
FOUNTOULAKIS KN, VIETA E, BOURAS C, NOTARIDIS G, GIANNAKOPOULOS P, KAPRINIS G, AKISKAL H

Assessing the cognitive impact of Alzheimer disease pathology and vascular burden in the aging brain: the Geneva experience
ACTA NEUROPATHOLOGICA
2007 vol. 113 pp. 1-12
GIANNAKOPOULOS P, GOLD G, KOVARI E, VON GUNTEN A, IMHOF A, BOURAS C, HOF PR

Identification of Alzheimer and vascular lesion thresholds for mixed dementia
BRAIN
2007 vol. 130 pp. 2830-2836
GOLD G, GIANNAKOPOULOS P, HERRMANN FR, BOURAS C, KOVARI E

Structured assessment of mental health status in psychogeriatrics: Validity of the French HoNOS65+
CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE
2007 vol. 52 pp. 37-45
CANUTO A, WEBER K, GOLD G, NOTARIDIS G, MICHON A, GIARDINI U, DELALOYE C, HERRMANN F, GIANNAKOPOULOS P

Distinction between perceptual and attentional processing in working memory tasks: A study of phase-locked and induced oscillatory brain dynamics
JOURNAL OF COGNITIVE NEUROSCIENCE
2007 vol. 19 pp. 158-172
DEIBER MP, MISSONNIER P, BERTRAND O, GOLD G, FAZIO-COSTA L, IBANEZ V, GIANNAKOPOULOS P

Morphological substrates of cognitive decline in nonagenarians and centenarians: A new paradigm?
JOURNAL OF THE NEUROLOGICAL SCIENCES
2007 vol. 257 pp. 72-79
IMHOF A, KOVARI E, VON GUNTEN A, GOLD G, RIVARA CB, HERRMANN FR, HOF PR, BOURAS C, GLANNAKOPOULOS P

Sorting out the clinical consequences of ischemic lesions in brain aging: A clinicopathological approach
JOURNAL OF THE NEUROLOGICAL SCIENCES
2007 vol. 257 pp. 17-22
GOLD G, KOVARI E, HOF PR, BOURAS C, GIANNAKOPOULOS P

Validation of clinical criteria for possible vascular dementia in the oldest-old
NEUROBIOLOGY OF AGING
2007 vol. 28 pp. 579-585
BACCHETTA JP, KOVARI E, MERLO M, CANUTO A, HERRMANN FR, BOURAS C, GOLD G, HOF PR, GIANNAKOPOULOS P

Cortical microinfarcts and demyelination affect cognition in cases at high risk for dementia
NEUROLOGY
2007 vol. 68 pp. 927-931
KOVARI E, GOLD G, HERRMANN FR, CANUTO A, HOF PR, BOURAS C, GIANNAKOPOULOS P

Stereological analysis of neuropil threads in the hippocampal formation: relationships with Alzheimer's disease neuronal pathology and cognition
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
2007 vol. 33 pp. 334-343
GIANNAKOPOULOS P, VON GUNTEN A, KOVARI E, GOLD G, HERRMANN FR, HOF PR, BOURAS C

Decreased infarct size after focal cerebral ischemia in mice chronically infected with Toxoplasma gondii.
NEUROSCIENCE
2007 vol. 150(3) pp. 537-546
ARSENIJEVIC D, DE BILBAO F, VALLET P, HEMPHILL A, GOTTSTEIN B, RICHARD D, GIANNAKOPOULOS P, LANGHANS W

Working memory load-related electroencephalographic parameters can differentiate progressive from stable mild cognitive impairment.
NEUROSCIENCE
2007 vol. 150(2) pp. 346-356
MISSONNIER P, DEIBER MP, GOLD G, HERRMANN FR, MILLET P, MICHON A, FAZIO-COSTA LARA, IBA—EZ V, GIANNAKOPOULOS P

Psychometric properties of the Doloplus-2 observational pain assessment scale and comparison to self-assessment in hospitalized elderly.
THE CLINICAL JOURNAL OF PAIN
2007 vol. 23(9) pp. 774-779
PAUTEX S, HERRMANN FR, MICHON A, GIANNAKOPOULOS P, GOLD G

Neural substrates of cognitive and behavioral deficits in atypical Alzheimer's disease
BRAIN RESEARCH REVIEWS
2006 vol. 51(2) pp. 176-211
VON GUNTEN ARMIN, BOURAS CONSTANTIN, K÷VARI ENIK÷, GIANNAKOPOULOS PANTELEIMON, HOF PATRICK R

Decreased theta event-related synchronization during working memory activation is associated with progressive mild cognitive impairment
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS
2006 vol. 22 pp. 250-259
MISSONNIER P, GOLD G, HERRMANN FR, FAZIO-COSTA LARA, MICHEL JP, DEIBER MP, MICHON A, GIANNAKOPOULOS P

Increased infarct size and lack of hyperphagic response after focal cerebral ischemia in peroxisome proliferator-activated receptor beta-deficient mice
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
2006 vol. 26 pp. 433-445
ARSENIJEVIC D, DE BILBAO F, PLAMONDON J, PARADIS E, VALLET P, RICHARD D, LANGHANS W, GIANNAKOPOULOS P

Frontal theta event-related synchronization: comparison of directed attention and working memory load effects
JOURNAL OF NEURAL TRANSMISSION
2006 vol. 113 pp. 1477-1486
MISSONNIER P, DEIBER MP, GOLD G, MILLET P, PUN MGF, FAZIO-COSTA L, GIANNAKOPOULOS P, IBANEZ V

Stereologic analysis of microvascular morphology in the elderly: Alzheimer disease pathology and cognitive status
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
2006 vol. 65 pp. 235-244
BOURAS C, KOVARI E, HERRMANN FR, RIVARA CB, BAILEY TL, VON GUNTEN A, HOF PR, GIANNAKOPOULOS P

Pain in severe dementia: Self-assessment or observational scales?
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
2006 vol. 54 pp. 1040-1045
PAUTEX S, MICHON A, GUEDIRA M, EMOND H, LE LOUS PAULETTE, SAMARAS D, MICHEL JP, HERRMANN FR, GIANNAKOPOULOS P, GOLD G

Collaboration entre gériatrie et psychiatrie-gériatrie : le modèle développé à Genève
L'ENCEPHALE
2006 vol. 32 Pt 4 pp. 1175-1177
MICHEL JEAN-PIERRE, GOLD GABRIEL, GIANNAKOPOULOS PANTELEIMON

Cognitive impact of neuronal pathology in the entorhinal cortex and CA1 field in Alzheimer's disease
NEUROBIOLOGY OF AGING
2006 vol. 27(2) pp. 270-277
VON GUNTEN ARMIN, KOVARI ENRIKO, BUSSIERE THIERRY, RIVARA CLAIRE-BENEDICTE, GOLD GABRIEL, BOURAS CONSTANTIN, HOF R. PATRICK, GIANNAKOPOULOS PANTELEIMON

Sustained astrocytic clusterin expression improves remodeling after brain ischemia
NEUROBIOLOGY OF DISEASE B
2006 vol. 22 pp. 274-283
IMHOF A, CHARNAY Y, VALLET PG, ARONOW B, KOVARI E, FRENCH LE, BOURAS C, GIANNAKOPOULOS P

Neuropathological analysis of an asymptomatic adult case with Dandy-Walker variant
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
2006 vol. 32(3) pp. 344-350
NOTARIDIS G, EBBING K, GIANNAKOPOULOS P, BOURAS C, K÷VARI E

Environmental reduplicative paramnesia in a case of atypical Alzheimerís disease
NEUROCASE : CASE STUDIES IN NEUROPSYCHOLOGY, NEUROPSYCHIATRY, AND BEHAVIOURAL NEUROLOGY
2005 vol. 11 pp. 216-229
VON GUNTEN A, MIKLOSSY J, SUVņ M.-L, HOF P.R, GIANNAKOPOULOS PANTELEIMON

Clinicopathological validation study of four sets of clinical criteria for vascular dementia
AMERICAN JOURNAL OF PSYCHIATRY
2002 vol. 159 pp. 82-87
GOLD G, BOURAS C, CANUTO A, BERGALLO MF, HERRMANN FR, HOF PR, MAYOR PA, MICHEL JP, GIANNAKOPOULOS P

The role of stimulus type in age-related changes of visual working memory
EXPERIMENTAL BRAIN RESEARCH
2002 vol. 146 pp. 172-183
LEONARDS U, IBANEZ V, GIANNAKOPOULOS P


Research's domains