DATABASE-RESEARCH | GROUP OF CLINICAL PATIENT RESEARCH | ||||||
Margitta SEECK | Head of group CV | Research subject | Members of the group |
Links about the group
Dr. M. SEECK HUG/ Dpt NEUCLID Serv Neurologie Rue Gabrielle-Perret-Gentil 4 1211 Genève 14 Suisse margitta.seeck@hcuge.ch Tel.: + 41 22 372 84 76 Fax: + 41 22 372 84 75 Comments Pages updated the 17.11.2015 |
Reseach's subject
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Group's publications
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Research's domains
Surgery and Epilepsy
Epilepsy surgery is an additional treatment option for patients (children and adults) suffering from pharmacoresistant epilepsy. In the context of presurgical epilepsy evaluation, 2 questions are of
major importance: 1) precise localization of the epileptogenic focus, 2) localization of vital cortex, which has to be spared during the operation. Related to these 2 issues, our patient oriented
research focuses on the development of non-invasive tools for focus and cortical function localization. Related to the latter issue, several projects addressing also more scientific aspects of cortical
processes are under way, including healthy volunteers, patients with scalp and intracranial electrodes. In particular patients with intracranial electrodes offer the unique opportunity to study
cognitive processes directly in the human brain, such as face processing, language processing or experiential phenomena.
Further areas of interest: (1) investigation of physiological and pathological processes by high resolution 128-channel scalp EEG, (2) how does epilepsy interfere with normal development in very young epileptic children and can that be halted by surgical treatment (in collaboration with the Neuropediatric groups of the university Hospitals of Geneva and Lausanne; Dr. E. Roulet-Perez), (3) coupling of fMRI with EEG in the analysis of physiological and pathological signals (collaboration with Neuroradiologie, University Hospital of Geneva, Dr. F. Lazeyras). Group's publications Exhaustive analysis of BH4 and dopamine biosynthesis genes in patients with Dopa-responsive dystonia. BRAIN 2009 vol. 132(Pt 7) pp. 1753-1763 CLOT F. AND AL. Selective changes in GABAA receptor subtypes in white matter neurons of patients with focal epilepsy. BRAIN 2009 vol. 132(Pt 9) pp. 2449-2463 LOUP F, PICARD F, YONEKAWA Y, WIESER HG, FRITSCHY JM Syndrome of transient headache and neurological deficits with CSF lymphocytosis (HaNDL) associated with recent human herpesvirus-6 infection CEPHALALGIA 2009 vol. 29(4) pp. 487-491 EMOND H, SCHNORF H, POLONI C, VULLIEMOZ S, LALIVE P.H. Symptomatic syringomyelia occurring as a late complication of posterior fossa medulloblastoma removal in infancy in a boy also suffering from scaphocephaly CHILD'S NERVOUS SYSTEM : CHNS : OFFICIAL JOURNAL OF THE INTERNATIONAL SOCIETY FOR PEDIATRIC NEUROSURGERY 2009 vol. 25(12) pp. 1633-1637 EL HASSANI Y, BURKHARDT K, DELAVELLE J, VARGAS MI, BOEX C, RILLIET B Accuracy of EEG source imaging of epileptic spikes in patients with large brain lesions. CLINICAL NEUROPHYSIOLOGY 2009 vol. 120(4) pp. 679-685 BRODBECK V, LASCANO AM, SPINELLI L, SEECK M, MICHEL CM Ecstatic epileptic seizures: a potential window on the neural basis for human self-awareness. EPILEPSY & BEHAVIOR 2009 vol. 16(3) pp. 539-546 PICARD F, CRAIG AD Neuropsychological disturbances in frontal lobe epilepsy due to mutated nicotinic receptors. EPILEPSY & BEHAVIOR 2009 vol. 14(2) pp. 354-359 PICARD F, PEGNA AJ, ARNTSBERG V, LUCAS N, KACZMAREK I, TODICA O, CHIRIACO C, SEECK M, BRODTKORB E Is benign myoclonic epilepsy of infancy truly idiopathic and generalized? EPILEPTIC DISORDERS : INTERNATIONAL EPILEPSY JOURNAL WITH VIDEOTAPE 2009 vol. 11(2) pp. 132-135 KORFF CM, JALLON P, LASCANO AM, MICHEL CM, SEECK M, HAENGGELI CA Reversible acquired epileptic frontal syndrome and CSWS suppression in a child with congenital hemiparesis treated by hemispherotomy. EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY 2009 vol. 13(5) pp. 430-438 KALLAY C, MAYOR-DUBOIS C, MAEDER-INGVAR M, SEECK M, DEBATISSE D, DEONNA T, ROULET-PEREZ F Psychiatric comorbidity in patients evaluated for chronic epilepsy: a differential role of the right hemisphere? EUROPEAN NEUROLOGY 2009 vol. 61(6) pp. 350-357 SPERLI F, RENTSCH D, DESPLAND PA, FOLETTI G, JALLON P, PICARD F, LANDIS T, SEECK M Increasing the diagnostic value of evoked potentials in multiple sclerosis by quantitative topographic analysis of multichannel recordings. JOURNAL OF CLINICAL NEUROPHYSIOLOGY : OFFICIAL PUBLICATION OF THE AMERICAN ELECTROENCEPHALOGRAPHIC SOCIETY 2009 vol. 26(5) pp. 316-325 LASCANO AM, BRODBECK V, LALIVE D'EPINAY PATRICE, CHOFFLON M, SEECK M, MICHEL CM Imaging compatible electrodes for continuous electroencephalogram monitoring in the intensive care unit. JOURNAL OF CLINICAL NEUROPSYCHOLOGY 2009 vol. 26(4) pp. 236-243 VULLIEMOZ S, PERRIG S, PELLISE D, VARGAS MI, GASCHE Y, IVES JR, SEECK M Arterial spin-labeling demonstrates ictal cortical hyperperfusion in epilepsy secondary to hemimegalencephaly. JOURNAL OF NEURORADIOLOGY. JOURNAL DE NEURORADIOLOGIE 2009 vol. 36(5) pp. 303-305 ALTRICHTER S, PENDSE N, WISSMEYER M, JAGERSBERG M, FEDERSPIEL A, VIALLON M, SEECK M, LOVBLAD KO The spatio-temporal mapping of epileptic networks: Combination of EEG-fMRI and EEG source imaging NEUROIMAGE 2009 vol. 46(3) pp. 834-843 VULLIEMOZ S. AND AL. Levetiracetam accumulation in renal failure causing myoclonic encephalopathy with triphasic waves. SEIZURE : THE JOURNAL OF THE BRITISH EPILEPSY ASSOCIATION 2009 vol. 18(5) pp. 376-378 VULLIEMOZ S, IWANOWSKI P, LANDIS T, JALLON P "Gourmand syndrome" in a child with pharmacoresistant epilepsy. EPILEPSY & BEHAVIOR 2008 vol. 13(2) pp. 413-415 KURIAN M, SCHMITT-MECHELKE T, KORFF CM, DELAVELLE J, SEECK M, LANDIS T The selective amobarbital test in the anterior choroidal artery: perfusion pattern assessed by intraarterial SPECT and prediction of postoperative verbal memory. EPILEPSY & BEHAVIOR 2008 vol. 12(3) pp. 445-455 VULLIEMOZ S, PEGNA A, ANNONI JM, YILMAZ H, WILLI JEAN-PIERRE, SPINELLI L, LANDIS T, SEECK M The Wada test in Austrian, Dutch, German, and Swiss epilepsy centers from 2000 to 2005: a review of 1421 procedures. EPILEPSY & BEHAVIOR 2008 vol. 13(1) pp. 83-89 HAAG A AND AL. Presurgical evaluation of epilepsy patients. MEDICINA (KAUNAS, LITHUANIA) 2008 vol. 44(8) pp. 585-592 GELZINIENE G, ENDZINIENE M, VAICIENE N, MAGISTRIS MR, SEECK M Temporal anterior encephalocele. NEUROLOGY 2008 vol. 71(16) pp. 1293-1293 VARGAS MI, VULLIEMOZ S, ROSSET A, SEECK M, DELAVELLE J Intracerebral recordings of nocturnal hyperkinetic seizures: Demonstration of a longer duration of the pre-seizure sleep spindle CLINICAL NEUROPHYSIOLOGY 2007 vol. 118 pp. 928-939 PICARD F, MEGEVAND P, MINOTTI L, KAHANE P, RYVLIN P, SEECK M, MICHEL CM, LANTZ G Multimodality imaging for focus localization in pediatric pharmacoresistant epilepsy EPILEPTIC DISORDERS : INTERNATIONAL EPILEPSY JOURNAL WITH VIDEOTAPE 2007 vol. 9(1) pp. 20-31 KURIAN M, SPINELLI L, DELAVELLE J, WILLI JP, VELAZQUEZ M, CHAVES V, HABRE W, MEAGHER-VILLEMURE K, ROULET E, VILLENEUVE JG, SEECK M Partial withdrawal of deeply inserted cochlear electrodes: observations of two patients EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY 2007 vol. 264 pp. 1369-1372 KOS MI, BOEX C, GUYOT JP, PELIZZONE M Implications of deep electrode insertion on cochlear implant fitting JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY 2007 vol. 8 pp. 69-83 GANI M, VALENTINI G, SIGRIST A, KOS MI, BOEX C Epilepsy and cerebellar ataxia associated with anti-glutamic acid decarboxylase antibodies JOURNAL OF NEUROLOGY, NEUROSURGERY, AND PSYCHIATRY 2007 vol. 78 pp. 187-189 VULLIEMOZ S, VANINI G, TRUFFERT A, CHIZZOLINI C, SEECK M Seizures during stroke thrombolysis heralding dramatic neurologic recovery. NEUROLOGY 2007 vol. 69(4) pp. 409-410 SEECK M, VULLIEMOZ S Direct intracranial recording of body-selective responses in human extrastriate visual cortex NEUROPSYCHOLOGIA 2007 vol. 45 pp. 2621-2625 POURTOIS G, PEELEN MV, SPINELLI L, SEECK M, VUILLEUMIER P Bilateral temporal lobe epilepsy in a patient with Turner syndrome mosaicism SEIZURE : THE JOURNAL OF THE BRITISH EPILEPSY ASSOCIATION 2007 vol. 16 pp. 261-265 VULLIEMOZ S, DAHOUN S, SEECK M High and low frequency electrical stimulation in non-lesional temporal lobe epilepsy SEIZURE : THE JOURNAL OF THE BRITISH EPILEPSY ASSOCIATION 2007 vol. 16 pp. 664-669 BOEX C, VULLIEMOZ S, SPINELLI L, POLIO C, SEECK M Professional occupation after cochlear implantation. THE JOURNAL OF LARYNGOLOGY AND OTOLOGY 2007 vol. 121(3) pp. 215-218 KOS MI, DEGIVE C, BOEX C, GUYOT JP Extent of preoperative abnormalities and focus lateralization predict postoperative normalization of contralateral 1H-magnetic resonance spectroscopy metabolite levels in patients with temporal lobe e pilepsy AMERICAN JOURNAL OF NEURORADIOLOGY 2006 vol. 27 pp. 1766-1769 LANTZ G, SEECK M, LAZEYRAS F An association between type 1 diabetes and idiopathic generalized epilepsy ANNALS OF NEUROLOGY 2006 vol. 59 pp. 728-728 VULLIEMOZ S, SEECK M Pregabalin-withdrawal encephalopathy and splenial edema ANNALS OF NEUROLOGY 2006 vol. 59 pp. 214-214 PRILIPKO O, DELAVELLE J, SEECK M Contralateral smile and laughter, but no mirth, induced by electrical stimulation of the cingulate cortex EPILEPSIA 2006 vol. 47 pp. 440-443 SPERLI F, SPINELLI L, POLLO C, SEECK M EEG source imaging in pediatric epilepsy surgery: A new perspective in presurgical workup EPILEPSIA 2006 vol. 47 pp. 981-990 SPERLI F, SPINELLI L, SEECK M, KURIAN M, MICHEL CM, LANTZ G Postictal but not interictal hemispatial neglect in patients with seizures of lateralized onset EPILEPSIA 2006 vol. 47 pp. 2046-2051 PRILIPKO O, SEECK M, MERMILLOD B, LANDIS T, PEGNA AJ Acoustic to electric pitch comparisons in cochlear implant subjects with residual hearing JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY : JARO 2006 vol. 7(2) pp. 110-124 BOEX C, BAUD L, COSENDAI G, SIGRIST A, KOS MI, PELIZZONE M Induction of an illusory shadow person NATURE 2006 vol. 443(7109) pp. 287-287 ARZY S., SEECK M., ORITIQUE S., SPINELLI L., BLANKE O. Speech arrest with stimulation may not reliably predict language deficit after epilepsy surgery NEUROLOGY 2006 vol. 66 pp. 592-594 SEECK M, PEGNA AJ, ORTIGUE S, SPINELLI L, DESSIBOURG CA, DELAVELLE J, BLANKE O, MICHEL CM, LANDIS T, VILLEMURE JG Etat de mal épileptique et neurodégénérescence : entre cirucuits et cercles vicieux REVUE MEDICALE DE LA SUISSE ROMANDE 2006 vol. 2(64) pp. 1185-1186 ROSSETTI A.O., PERRIG S., LANDIS T., DESPLAND P.-A., SEECK M. Activité professionnelle des utilisateurs d'implant cochléaire REVUE MÉDICALE SUISSE 2006 vol. 2(81) pp. 2226-2228 KOS M-I., DEGIVE C., BOEX C., MAIRE R., GUYOT J.-P. Measurements of electrode position inside the cochlea for different cochlear impkant systems ACTA OTO-LARYNGOLOGICA 2005 vol. 125 pp. 474-480 KOS MARIA IZABEL, BOEX COLETTE, SIGRIST A., GUYOT JEAN-PHILIPPE, PELIZZONE MARCO FMRI evidence for activation of multiple cortical regions in the primary auditory cortex of deaf subjects users of multichannel cochlear implants. CEREBRAL CORTEX 2005 vol. 15 pp. 40-48 SEGHIER MOHAMED, BOEX COLETTE, LAZEYRAS FRANCOIS, SIGRIST A., PELIZZONE MARCO Reversible Cytotoxic Edema in the Splenium of the Corpus Callosum Related to Antiepileptic Treatment:Report of Two Cases and Literature Review. EPILEPSIA 2005 vol. 46(10) pp. 1633-1636 PRILIPKO OLGA, DELAVELLE JACQUELINE, LAZEYRAS FRANCOIS, SEECK MARGITTA Subcortical Nuclei Volumetry in Idiopathic Generalized Epilepsy. EPILEPSIA 2005 vol. 46 pp. 1642-1645 SEECK MARGITTA, DREIFUSS SYLVAIN, LANTZ GORAN, JALLON PIERRE-MARIE, FOLETTI GIOVANNI, DESPLAND PAUL-ANDRE, DELAVELLE JACQUELINE, LAZEYRAS FRANCOIS Orthostatic intolerance and syncope associated with Chiari type I malformation. JOURNAL OF NEUROLOGY, NEUROSURGERY, AND PSYCHIATRY 2005 vol. 76(7) pp. 1034-1036 PRILIPKO O, DEHDASHTI AR, ZAIM S, SEECK M Linking Out-of-Body Experience and Self Processing to Mental Own-Body Imagery at the Temporoparietal Junction. JOURNAL OF NEUROSCIENCE 2005 vol. 25 pp. 550-557 BLANKE OLAF, MOHR CHRISTINE, MICHEL CHRISTOPH, PASCUAL-LEONE ALVARO, BRUGGER PETER, SEECK MARGITTA, LANDIS THEODOR, THUT GREGOR Epileptic source localization with high density EEG : how many electrodes are needed ? CLINICAL NEUROPHYSIOLOGY 2003 vol. 114 pp. 63-69 LANTZ G, GRAVE DE PERALTA MENENDEZ R, SPINELLI L, SEECK M, MICHEL CM Stimulating illusory own-body perceptions. NATURE 2002 vol. 419 pp. 269-270 BLANKE O, ORTIGUE S, LANDIS T, SEECK M EEG-Linked functional magnetic resonance imaging in epilepsy and cognitive neurophysiology JOURNAL OF CLINICAL NEUROPHYSIOLOGY : OFFICIAL PUBLICATION OF THE AMERICAN ELECTROENCEPHALOGRAPHIC SOCIETY 2000 vol. 17(1) pp. 43-58 SCHOMER DL, BONMASSAR G, LAZEYRAS FRANCOIS, SEECK MAGRITTA, BLUM HEIDI ANTONIA, ANAMI K, SCHWARTZ D, BELLIVEAU JW, IVES J Non-invasive epileptic focus localization using EEG-triggered functional MRI and electromagnetic tomography ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY 1998 vol. vol. 106 pp. 508-512 SEECK M, LAZEYRAS F, MICHEL CM, BLANKE O, GERICKE CA, IVES J, DELAVELLE J, GOLAY X, HAENGGELI CA, DE TRIBOLET N, LANDIS T Evidence for rapid face recognition from human scalp and intracranial electrodes NEUROREPORT 1997 vol. 8 pp. 2749-2754 SEECK MAGRITTA, MICHEL CHRISTOPH, MAINWARING N, COSGROVE R, BLUME H, IVES J, LANDIS THEODOR, SCHOMER DL Research's domains |