Margitta SEECK  Head of group CV  Members of the group

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Dr. M. SEECK
HUG/ Dpt NEUCLID
Serv Neurologie
Rue Gabrielle-Perret-Gentil 4
1211 Genève 14
Suisse

margitta.seeck@hcuge.ch

Tel.: + 41 22 372 84 76
Fax: + 41 22 372 84 75




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Pages updated the 17.11.2015
Reseach's subject | Group's publications | Research's domains

Surgery and Epilepsy

Epilepsy surgery is an additional treatment option for patients (children and adults) suffering from pharmacoresistant epilepsy. In the context of presurgical epilepsy evaluation, 2 questions are of major importance: 1) precise localization of the epileptogenic focus, 2) localization of vital cortex, which has to be spared during the operation. Related to these 2 issues, our patient oriented research focuses on the development of non-invasive tools for focus and cortical function localization. Related to the latter issue, several projects addressing also more scientific aspects of cortical processes are under way, including healthy volunteers, patients with scalp and intracranial electrodes. In particular patients with intracranial electrodes offer the unique opportunity to study cognitive processes directly in the human brain, such as face processing, language processing or experiential phenomena.
Further areas of interest:
(1) investigation of physiological and pathological processes by high resolution 128-channel scalp EEG,
(2) how does epilepsy interfere with normal development in very young epileptic children and can that be halted by surgical treatment (in collaboration with the Neuropediatric groups of the university Hospitals of Geneva and Lausanne; Dr. E. Roulet-Perez),
(3) coupling of fMRI with EEG in the analysis of physiological and pathological signals (collaboration with Neuroradiologie, University Hospital of Geneva, Dr. F. Lazeyras).




Group's publications

Exhaustive analysis of BH4 and dopamine biosynthesis genes in patients with Dopa-responsive dystonia.
BRAIN
2009 vol. 132(Pt 7) pp. 1753-1763
CLOT F. AND AL.

Selective changes in GABAA receptor subtypes in white matter neurons of patients with focal epilepsy.
BRAIN
2009 vol. 132(Pt 9) pp. 2449-2463
LOUP F, PICARD F, YONEKAWA Y, WIESER HG, FRITSCHY JM

Syndrome of transient headache and neurological deficits with CSF lymphocytosis (HaNDL) associated with recent human herpesvirus-6 infection
CEPHALALGIA
2009 vol. 29(4) pp. 487-491
EMOND H, SCHNORF H, POLONI C, VULLIEMOZ S, LALIVE P.H.

Symptomatic syringomyelia occurring as a late complication of posterior fossa medulloblastoma removal in infancy in a boy also suffering from scaphocephaly
CHILD'S NERVOUS SYSTEM : CHNS : OFFICIAL JOURNAL OF THE INTERNATIONAL SOCIETY FOR PEDIATRIC NEUROSURGERY
2009 vol. 25(12) pp. 1633-1637
EL HASSANI Y, BURKHARDT K, DELAVELLE J, VARGAS MI, BOEX C, RILLIET B

Accuracy of EEG source imaging of epileptic spikes in patients with large brain lesions.
CLINICAL NEUROPHYSIOLOGY
2009 vol. 120(4) pp. 679-685
BRODBECK V, LASCANO AM, SPINELLI L, SEECK M, MICHEL CM

Ecstatic epileptic seizures: a potential window on the neural basis for human self-awareness.
EPILEPSY & BEHAVIOR
2009 vol. 16(3) pp. 539-546
PICARD F, CRAIG AD

Neuropsychological disturbances in frontal lobe epilepsy due to mutated nicotinic receptors.
EPILEPSY & BEHAVIOR
2009 vol. 14(2) pp. 354-359
PICARD F, PEGNA AJ, ARNTSBERG V, LUCAS N, KACZMAREK I, TODICA O, CHIRIACO C, SEECK M, BRODTKORB E

Is benign myoclonic epilepsy of infancy truly idiopathic and generalized?
EPILEPTIC DISORDERS : INTERNATIONAL EPILEPSY JOURNAL WITH VIDEOTAPE
2009 vol. 11(2) pp. 132-135
KORFF CM, JALLON P, LASCANO AM, MICHEL CM, SEECK M, HAENGGELI CA

Reversible acquired epileptic frontal syndrome and CSWS suppression in a child with congenital hemiparesis treated by hemispherotomy.
EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY
2009 vol. 13(5) pp. 430-438
KALLAY C, MAYOR-DUBOIS C, MAEDER-INGVAR M, SEECK M, DEBATISSE D, DEONNA T, ROULET-PEREZ F

Psychiatric comorbidity in patients evaluated for chronic epilepsy: a differential role of the right hemisphere?
EUROPEAN NEUROLOGY
2009 vol. 61(6) pp. 350-357
SPERLI F, RENTSCH D, DESPLAND PA, FOLETTI G, JALLON P, PICARD F, LANDIS T, SEECK M

Increasing the diagnostic value of evoked potentials in multiple sclerosis by quantitative topographic analysis of multichannel recordings.
JOURNAL OF CLINICAL NEUROPHYSIOLOGY : OFFICIAL PUBLICATION OF THE AMERICAN ELECTROENCEPHALOGRAPHIC SOCIETY
2009 vol. 26(5) pp. 316-325
LASCANO AM, BRODBECK V, LALIVE D'EPINAY PATRICE, CHOFFLON M, SEECK M, MICHEL CM

Imaging compatible electrodes for continuous electroencephalogram monitoring in the intensive care unit.
JOURNAL OF CLINICAL NEUROPSYCHOLOGY
2009 vol. 26(4) pp. 236-243
VULLIEMOZ S, PERRIG S, PELLISE D, VARGAS MI, GASCHE Y, IVES JR, SEECK M

Arterial spin-labeling demonstrates ictal cortical hyperperfusion in epilepsy secondary to hemimegalencephaly.
JOURNAL OF NEURORADIOLOGY. JOURNAL DE NEURORADIOLOGIE
2009 vol. 36(5) pp. 303-305
ALTRICHTER S, PENDSE N, WISSMEYER M, JAGERSBERG M, FEDERSPIEL A, VIALLON M, SEECK M, LOVBLAD KO

The spatio-temporal mapping of epileptic networks: Combination of EEG-fMRI and EEG source imaging
NEUROIMAGE
2009 vol. 46(3) pp. 834-843
VULLIEMOZ S. AND AL.

Levetiracetam accumulation in renal failure causing myoclonic encephalopathy with triphasic waves.
SEIZURE : THE JOURNAL OF THE BRITISH EPILEPSY ASSOCIATION
2009 vol. 18(5) pp. 376-378
VULLIEMOZ S, IWANOWSKI P, LANDIS T, JALLON P

"Gourmand syndrome" in a child with pharmacoresistant epilepsy.
EPILEPSY & BEHAVIOR
2008 vol. 13(2) pp. 413-415
KURIAN M, SCHMITT-MECHELKE T, KORFF CM, DELAVELLE J, SEECK M, LANDIS T

The selective amobarbital test in the anterior choroidal artery: perfusion pattern assessed by intraarterial SPECT and prediction of postoperative verbal memory.
EPILEPSY & BEHAVIOR
2008 vol. 12(3) pp. 445-455
VULLIEMOZ S, PEGNA A, ANNONI JM, YILMAZ H, WILLI JEAN-PIERRE, SPINELLI L, LANDIS T, SEECK M

The Wada test in Austrian, Dutch, German, and Swiss epilepsy centers from 2000 to 2005: a review of 1421 procedures.
EPILEPSY & BEHAVIOR
2008 vol. 13(1) pp. 83-89
HAAG A AND AL.

Presurgical evaluation of epilepsy patients.
MEDICINA (KAUNAS, LITHUANIA)
2008 vol. 44(8) pp. 585-592
GELZINIENE G, ENDZINIENE M, VAICIENE N, MAGISTRIS MR, SEECK M

Temporal anterior encephalocele.
NEUROLOGY
2008 vol. 71(16) pp. 1293-1293
VARGAS MI, VULLIEMOZ S, ROSSET A, SEECK M, DELAVELLE J

Intracerebral recordings of nocturnal hyperkinetic seizures: Demonstration of a longer duration of the pre-seizure sleep spindle
CLINICAL NEUROPHYSIOLOGY
2007 vol. 118 pp. 928-939
PICARD F, MEGEVAND P, MINOTTI L, KAHANE P, RYVLIN P, SEECK M, MICHEL CM, LANTZ G

Multimodality imaging for focus localization in pediatric pharmacoresistant epilepsy
EPILEPTIC DISORDERS : INTERNATIONAL EPILEPSY JOURNAL WITH VIDEOTAPE
2007 vol. 9(1) pp. 20-31
KURIAN M, SPINELLI L, DELAVELLE J, WILLI JP, VELAZQUEZ M, CHAVES V, HABRE W, MEAGHER-VILLEMURE K, ROULET E, VILLENEUVE JG, SEECK M

Partial withdrawal of deeply inserted cochlear electrodes: observations of two patients
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
2007 vol. 264 pp. 1369-1372
KOS MI, BOEX C, GUYOT JP, PELIZZONE M

Implications of deep electrode insertion on cochlear implant fitting
JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY
2007 vol. 8 pp. 69-83
GANI M, VALENTINI G, SIGRIST A, KOS MI, BOEX C

Epilepsy and cerebellar ataxia associated with anti-glutamic acid decarboxylase antibodies
JOURNAL OF NEUROLOGY, NEUROSURGERY, AND PSYCHIATRY
2007 vol. 78 pp. 187-189
VULLIEMOZ S, VANINI G, TRUFFERT A, CHIZZOLINI C, SEECK M

Seizures during stroke thrombolysis heralding dramatic neurologic recovery.
NEUROLOGY
2007 vol. 69(4) pp. 409-410
SEECK M, VULLIEMOZ S

Direct intracranial recording of body-selective responses in human extrastriate visual cortex
NEUROPSYCHOLOGIA
2007 vol. 45 pp. 2621-2625
POURTOIS G, PEELEN MV, SPINELLI L, SEECK M, VUILLEUMIER P

Bilateral temporal lobe epilepsy in a patient with Turner syndrome mosaicism
SEIZURE : THE JOURNAL OF THE BRITISH EPILEPSY ASSOCIATION
2007 vol. 16 pp. 261-265
VULLIEMOZ S, DAHOUN S, SEECK M

High and low frequency electrical stimulation in non-lesional temporal lobe epilepsy
SEIZURE : THE JOURNAL OF THE BRITISH EPILEPSY ASSOCIATION
2007 vol. 16 pp. 664-669
BOEX C, VULLIEMOZ S, SPINELLI L, POLIO C, SEECK M

Professional occupation after cochlear implantation.
THE JOURNAL OF LARYNGOLOGY AND OTOLOGY
2007 vol. 121(3) pp. 215-218
KOS MI, DEGIVE C, BOEX C, GUYOT JP

Extent of preoperative abnormalities and focus lateralization predict postoperative normalization of contralateral 1H-magnetic resonance spectroscopy metabolite levels in patients with temporal lobe e pilepsy
AMERICAN JOURNAL OF NEURORADIOLOGY
2006 vol. 27 pp. 1766-1769
LANTZ G, SEECK M, LAZEYRAS F

An association between type 1 diabetes and idiopathic generalized epilepsy
ANNALS OF NEUROLOGY
2006 vol. 59 pp. 728-728
VULLIEMOZ S, SEECK M

Pregabalin-withdrawal encephalopathy and splenial edema
ANNALS OF NEUROLOGY
2006 vol. 59 pp. 214-214
PRILIPKO O, DELAVELLE J, SEECK M

Contralateral smile and laughter, but no mirth, induced by electrical stimulation of the cingulate cortex
EPILEPSIA
2006 vol. 47 pp. 440-443
SPERLI F, SPINELLI L, POLLO C, SEECK M

EEG source imaging in pediatric epilepsy surgery: A new perspective in presurgical workup
EPILEPSIA
2006 vol. 47 pp. 981-990
SPERLI F, SPINELLI L, SEECK M, KURIAN M, MICHEL CM, LANTZ G

Postictal but not interictal hemispatial neglect in patients with seizures of lateralized onset
EPILEPSIA
2006 vol. 47 pp. 2046-2051
PRILIPKO O, SEECK M, MERMILLOD B, LANDIS T, PEGNA AJ

Acoustic to electric pitch comparisons in cochlear implant subjects with residual hearing
JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY : JARO
2006 vol. 7(2) pp. 110-124
BOEX C, BAUD L, COSENDAI G, SIGRIST A, KOS MI, PELIZZONE M

Induction of an illusory shadow person
NATURE
2006 vol. 443(7109) pp. 287-287
ARZY S., SEECK M., ORITIQUE S., SPINELLI L., BLANKE O.

Speech arrest with stimulation may not reliably predict language deficit after epilepsy surgery
NEUROLOGY
2006 vol. 66 pp. 592-594
SEECK M, PEGNA AJ, ORTIGUE S, SPINELLI L, DESSIBOURG CA, DELAVELLE J, BLANKE O, MICHEL CM, LANDIS T, VILLEMURE JG

Etat de mal épileptique et neurodégénérescence : entre cirucuits et cercles vicieux
REVUE MEDICALE DE LA SUISSE ROMANDE
2006 vol. 2(64) pp. 1185-1186
ROSSETTI A.O., PERRIG S., LANDIS T., DESPLAND P.-A., SEECK M.

Activité professionnelle des utilisateurs d'implant cochléaire
REVUE MÉDICALE SUISSE
2006 vol. 2(81) pp. 2226-2228
KOS M-I., DEGIVE C., BOEX C., MAIRE R., GUYOT J.-P.

Measurements of electrode position inside the cochlea for different cochlear impkant systems
ACTA OTO-LARYNGOLOGICA
2005 vol. 125 pp. 474-480
KOS MARIA IZABEL, BOEX COLETTE, SIGRIST A., GUYOT JEAN-PHILIPPE, PELIZZONE MARCO

FMRI evidence for activation of multiple cortical regions in the primary auditory cortex of deaf subjects users of multichannel cochlear implants.
CEREBRAL CORTEX
2005 vol. 15 pp. 40-48
SEGHIER MOHAMED, BOEX COLETTE, LAZEYRAS FRANCOIS, SIGRIST A., PELIZZONE MARCO

Reversible Cytotoxic Edema in the Splenium of the Corpus Callosum Related to Antiepileptic Treatment:Report of Two Cases and Literature Review.
EPILEPSIA
2005 vol. 46(10) pp. 1633-1636
PRILIPKO OLGA, DELAVELLE JACQUELINE, LAZEYRAS FRANCOIS, SEECK MARGITTA

Subcortical Nuclei Volumetry in Idiopathic Generalized Epilepsy.
EPILEPSIA
2005 vol. 46 pp. 1642-1645
SEECK MARGITTA, DREIFUSS SYLVAIN, LANTZ GORAN, JALLON PIERRE-MARIE, FOLETTI GIOVANNI, DESPLAND PAUL-ANDRE, DELAVELLE JACQUELINE, LAZEYRAS FRANCOIS

Orthostatic intolerance and syncope associated with Chiari type I malformation.
JOURNAL OF NEUROLOGY, NEUROSURGERY, AND PSYCHIATRY
2005 vol. 76(7) pp. 1034-1036
PRILIPKO O, DEHDASHTI AR, ZAIM S, SEECK M

Linking Out-of-Body Experience and Self Processing to Mental Own-Body Imagery at the Temporoparietal Junction.
JOURNAL OF NEUROSCIENCE
2005 vol. 25 pp. 550-557
BLANKE OLAF, MOHR CHRISTINE, MICHEL CHRISTOPH, PASCUAL-LEONE ALVARO, BRUGGER PETER, SEECK MARGITTA, LANDIS THEODOR, THUT GREGOR

Epileptic source localization with high density EEG : how many electrodes are needed ?
CLINICAL NEUROPHYSIOLOGY
2003 vol. 114 pp. 63-69
LANTZ G, GRAVE DE PERALTA MENENDEZ R, SPINELLI L, SEECK M, MICHEL CM

Stimulating illusory own-body perceptions.
NATURE
2002 vol. 419 pp. 269-270
BLANKE O, ORTIGUE S, LANDIS T, SEECK M

EEG-Linked functional magnetic resonance imaging in epilepsy and cognitive neurophysiology
JOURNAL OF CLINICAL NEUROPHYSIOLOGY : OFFICIAL PUBLICATION OF THE AMERICAN ELECTROENCEPHALOGRAPHIC SOCIETY
2000 vol. 17(1) pp. 43-58
SCHOMER DL, BONMASSAR G, LAZEYRAS FRANCOIS, SEECK MAGRITTA, BLUM HEIDI ANTONIA, ANAMI K, SCHWARTZ D, BELLIVEAU JW, IVES J

Non-invasive epileptic focus localization using EEG-triggered functional MRI and electromagnetic tomography
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY
1998 vol. vol. 106 pp. 508-512
SEECK M, LAZEYRAS F, MICHEL CM, BLANKE O, GERICKE CA, IVES J, DELAVELLE J, GOLAY X, HAENGGELI CA, DE TRIBOLET N, LANDIS T

Evidence for rapid face recognition from human scalp and intracranial electrodes
NEUROREPORT
1997 vol. 8 pp. 2749-2754
SEECK MAGRITTA, MICHEL CHRISTOPH, MAINWARING N, COSGROVE R, BLUME H, IVES J, LANDIS THEODOR, SCHOMER DL


Research's domains